RAB35 and GNPAT

Data Source:
HPRD (two hybrid)

		RAB35	GNPAT
Description		RAB35, member RAS oncogene family	glyceronephosphate O-acyltransferase
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Clathrin-coated Pit Endosome Membrane Clathrin-coated Vesicle Membrane Cell Projection Membrane Melanosome Intercellular Bridge Clathrin-coated Endocytic Vesicle Recycling Endosome Membrane Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane	Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol Membrane Mitochondrial Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Phosphatidylinositol-4,5-bisphosphate Binding GDP Binding	Glycerone-phosphate O-acyltransferase Activity
	Biological Process	Mitotic Cytokinesis Protein Localization Protein Transport Endosomal Transport Antigen Processing And Presentation Neuron Projection Development Endocytic Recycling Rab Protein Signal Transduction Protein Localization To Endosome Plasma Membrane To Endosome Transport Cellular Response To Nerve Growth Factor Stimulus	Protein Targeting To Peroxisome Fatty Acid Metabolic Process Phosphatidic Acid Biosynthetic Process Synapse Assembly Response To Nutrient Ether Lipid Biosynthetic Process Phospholipid Biosynthetic Process Cerebellum Morphogenesis Paranodal Junction Assembly Response To Drug Response To Starvation Membrane Organization Response To Fatty Acid
Pathways		TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Synthesis of PA Plasmalogen biosynthesis Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases			Rhizomelic chondrodysplasia punctata, including: Rhizomelic chondrodysplasia punctata, type I (RCDP1); Rhizomelic chondrodysplasia punctata, type II (RCDP2); Rhizomelic chondrodysplasia punctata, type III (RCDP3)
GWAS		Heel bone mineral density ( 30598549)
Interacting Genes		9 interacting genes: APP CALCOCO2 CBR3 GNPAT IDH3B PTPRS TBPL1 TRIM54 WDCP	6 interacting genes: AGPS GPR3 HSPB1 PEX5 RAB35 VDR
Entrez ID		11021	8443
HPRD ID		05010	04120
Ensembl ID		ENSG00000111737	ENSG00000116906
Uniprot IDs		Q15286	O15228
PDB IDs		3TW8 6EKK 6IF2 6IF3
Enriched GO Terms of Interacting Partners?
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