RAB35 and IDH3B

Data Source:
HPRD (two hybrid)

		RAB35	IDH3B
Description		RAB35, member RAS oncogene family	isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
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GO Annotations	Cellular Component	Cytosol Plasma Membrane Clathrin-coated Pit Endosome Membrane Clathrin-coated Vesicle Membrane Cell Projection Membrane Melanosome Intercellular Bridge Clathrin-coated Endocytic Vesicle Recycling Endosome Membrane Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane	Nucleus Mitochondrion Mitochondrial Matrix
	Molecular Function	GTPase Activity Protein Binding GTP Binding Phosphatidylinositol-4,5-bisphosphate Binding GDP Binding	Magnesium Ion Binding Isocitrate Dehydrogenase (NAD+) Activity Electron Transfer Activity NAD Binding
	Biological Process	Mitotic Cytokinesis Protein Localization Protein Transport Endosomal Transport Antigen Processing And Presentation Neuron Projection Development Endocytic Recycling Rab Protein Signal Transduction Protein Localization To Endosome Plasma Membrane To Endosome Transport Cellular Response To Nerve Growth Factor Stimulus	Tricarboxylic Acid Cycle Isocitrate Metabolic Process Electron Transport Chain
Pathways		TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Citric acid cycle (TCA cycle)
Drugs			NADH
Diseases			Retinitis pigmentosa (RP)
GWAS		Heel bone mineral density ( 30598549)
Interacting Genes		9 interacting genes: APP CALCOCO2 CBR3 GNPAT IDH3B PTPRS TBPL1 TRIM54 WDCP	6 interacting genes: ATXN2 IDH3A IDH3G MAPK6 PRMT1 RAB35
Entrez ID		11021	3420
HPRD ID		05010	05163
Ensembl ID		ENSG00000111737	ENSG00000101365
Uniprot IDs		Q15286	A0A087WZN1 A0A087X2E5 O43837
PDB IDs		3TW8 6EKK 6IF2 6IF3	6KDE 6KDF 6KDY 6KE3
Enriched GO Terms of Interacting Partners?
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