C7orf25 and DACT1

Data Source:
BioGRID (two hybrid)

		C7orf25	DACT1
Description		chromosome 7 open reading frame 25	dishevelled binding antagonist of beta catenin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Cytoplasm Cytosol Beta-catenin Destruction Complex Synapse
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Factor Binding Protein Kinase C Binding Protein Binding Beta-catenin Binding Histone Deacetylase Binding Protein Kinase A Binding Delta-catenin Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Wnt Signaling Pathway Neural Tube Development Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Regulation Of Protein Stability Negative Regulation Of Protein Binding Positive Regulation Of Protein Binding Positive Regulation Of Protein Catabolic Process Negative Regulation Of JNK Cascade Embryonic Hindgut Morphogenesis Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway Regulation Of Nodal Signaling Pathway Positive Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Beta-catenin-TCF Complex Assembly Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways			Degradation of DVL
Drugs
Diseases
GWAS		Asthma ( 29273806) Ceramide levels (C24:0) ( 32489964)	Brain morphology (MOSTest) ( 32665545) Colorectal cancer or advanced adenoma ( 30510241) Dentate gyrus granule cell layer volume (corrected for total hippocampal volume) ( 30279459) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hippocampal subfield CA1 volume (corrected for total hippocampal volume) ( 30279459) Hippocampal tail volume (corrected for total hippocampal volume) ( 30279459) Metabolite levels ( 23823483) Occipital lobe volume ( 31396565) Parietal lobe volume ( 31396565)
Interacting Genes		20 interacting genes: BRD4 CEP70 CRYM DACT1 EZH2 FRA10AC1 FYN FZR1 GTPBP1 HAP1 HEXD MTOR MX1 NGEF PTN RASSF1 RPL36AL SF3B2 TARS1 UBE2D1	6 interacting genes: APPL1 C7orf25 CSNK2B PPP1CC SH3GL2 TK1
Entrez ID		79020	51339
HPRD ID		09861	09709
Ensembl ID		ENSG00000136197	ENSG00000165617
Uniprot IDs		Q9BPX7	Q9NYF0
PDB IDs
Enriched GO Terms of Interacting Partners?
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