STIP1 and CLCN1

Data Source:
BioGRID (pull down, affinity chromatography technology)

		STIP1	CLCN1
Description		stress induced phosphoprotein 1	chloride voltage-gated channel 1
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GO Annotations	Cellular Component	Nucleus Golgi Apparatus Cytosol Protein-containing Complex Chaperone Complex	Plasma Membrane Integral Component Of Plasma Membrane Chloride Channel Complex Sarcolemma
	Molecular Function	RNA Binding Protein Binding Protein C-terminus Binding Hsp70 Protein Binding Chaperone Binding Hsp90 Protein Binding	Voltage-gated Chloride Channel Activity Protein Binding Protein Homodimerization Activity
	Biological Process	Cellular Response To Interleukin-7	Chloride Transport Muscle Contraction Neuronal Action Potential Propagation Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Chloride Transmembrane Transport
Pathways		HSP90 chaperone cycle for steroid hormone receptors (SHR)	Stimuli-sensing channels
Drugs		Copper
Diseases			Myotonia congenita, including: Autosomal dominant myotonia congenita (Thomsen disease); Autosomal recessive myotonia congenita (Becker disease); Fluctuating myotonia congenita; Myotonia levoir
GWAS		Attention deficit hyperactivity disorder ( 21784300) Crohn's disease ( 28067908) Fruit consumption ( 32066663)
Interacting Genes		23 interacting genes: ACD ACVR1 AIP APP CDC37 CLCN1 CLK1 EGFR ERBB2 FKBP4 FKBP5 HSP90AA1 HSPA14 HSPA1A HSPA1B HSPA8 LMO2 MAP3K8 POT1 PRNP PTGES3 SUMO2 SUMO4	7 interacting genes: AHSA1 APPBP2 CIDEB FAM9B FKBP8 PRDM5 STIP1
Entrez ID		10963	1180
HPRD ID		05454	00320
Ensembl ID		ENSG00000168439	ENSG00000188037
Uniprot IDs		P31948 V9HW72	P35523
PDB IDs		1ELR 1ELW 2LNI 2NC9 3ESK 3FWV	6COY 6COZ 6QV6 6QVB 6QVC 6QVD 6QVU
Enriched GO Terms of Interacting Partners?
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