C11orf58 and SNCAIP

Data Source:
BioGRID (two hybrid)

		C11orf58	SNCAIP
Description		chromosome 11 open reading frame 58	synuclein alpha interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component	Nucleoplasm Cytoplasm Cytosol Synaptic Vesicle Cytoplasmic Ribonucleoprotein Granule Presynaptic Membrane Neuronal Cell Body
	Molecular Function	Molecular_function	Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding
	Biological Process	Biological_process	Cell Death Dopamine Metabolic Process Cellular Protein Metabolic Process Regulation Of Neurotransmitter Secretion Regulation Of Inclusion Body Assembly
Pathways			Amyloid fiber formation
Drugs
Diseases
GWAS		Chronotype ( 30696823) Coronary artery disease ( 33020668) Femoral neck bone mineral density ( 29499414) Heel bone mineral density ( 30598549 28869591) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Lumbar spine bone mineral density ( 29499414) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494)	Chronic kidney disease (end stage renal disease vs. normal eGFR) in type 1 diabetes ( 31537649) Delirium ( 29631748) Depressive symptoms x independent stressful life events interaction (2df test) ( 30718454) Event free survival in diffuse large B-cell lymphoma treated with immunochemotherapy ( 26460308) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Mood disorder and prion disease ( 25897833) Response to paclitaxel in ovarian cancer (Caspase 3/7 EC50) ( 27047539)
Interacting Genes		16 interacting genes: A2M CEP126 EEF1G FBN3 MBTPS1 POLR2C PTN RNF19A RPLP1 SEMA5B SF3B1 SHC1 SLC44A1 SNCAIP TRA2A ZBTB48	19 interacting genes: AGXT C11orf58 GET4 GSK3B NUB1 NUDT21 PIN1 PINK1 PPHLN1 PRKN PTN RNF19A SEPTIN4 SH2D3C SIAH1 SIAH2 SNCA TLE5 UBB
Entrez ID		10944	9627
HPRD ID		18069	04804
Ensembl ID		ENSG00000110696	ENSG00000064692
Uniprot IDs		O00193	B7Z616 B7Z995 Q6L981 Q6L983 Q9Y6H5
PDB IDs			2KES
Enriched GO Terms of Interacting Partners?
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