MSL3 and KAT8

Data Source:
BioGRID (affinity chromatography technology, pull down)

		MSL3	KAT8
Description		MSL complex subunit 3	lysine acetyltransferase 8
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GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm NuA4 Histone Acetyltransferase Complex MSL Complex	Histone Acetyltransferase Complex Kinetochore Nucleus Nucleoplasm Nuclear Matrix MLL1 Complex MSL Complex
	Molecular Function	DNA Binding Protein Binding Methylated Histone Binding Histone Acetyltransferase Activity (H4-K16 Specific)	Transcription Coregulator Activity Histone Acetyltransferase Activity Protein Binding Transcription Factor Binding Acetyltransferase Activity Enzyme Binding Methylated Histone Binding Histone Binding Histone Acetyltransferase Activity (H4-K5 Specific) Histone Acetyltransferase Activity (H4-K8 Specific) Metal Ion Binding Histone Acetyltransferase Activity (H4-K16 Specific)
	Biological Process	Chromatin Silencing Regulation Of Transcription, DNA-templated Histone Acetylation Histone Deacetylation Histone H4 Acetylation Histone H2A Acetylation Histone H4-K16 Acetylation	Regulation Of Autophagy Histone Acetylation Myeloid Cell Differentiation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		HATs acetylate histones	HATs acetylate histones
Drugs
Diseases
GWAS			Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Body mass index ( 25673413) Family history of Alzheimer's disease ( 30617256) Parkinson's disease ( 28892059) Triglyceride levels ( 32154731)
Interacting Genes		8 interacting genes: APP CDK6 H3-4 H3C1 H4-16 H4C1 KAT8 PAF1	12 interacting genes: ATM BAZ2A FOXP3 H4C1 KANSL1 KMT2A MSL3 PAF1 PLAU RNF2 TP53 TP53BP1
Entrez ID		10943	84148
HPRD ID		05344	11381
Ensembl ID		ENSG00000005302	ENSG00000103510
Uniprot IDs		Q8N5Y2	Q9H7Z6
PDB IDs		2Y0N 3OA6 3OB9	2GIV 2PQ8 2Y0M 3QAH 3TOA 3TOB 4DNC 5H43 5J8C 5J8F 5WCI 6BA2 6BA4 6CT2 6OIN 6OIO 6OIP 6OIQ 6OIR 6OWH 6OWI 6PD8 6PD9 6PDA 6PDB 6PDC 6PDD 6PDE 6PDF 6PDG 7CMR
Enriched GO Terms of Interacting Partners?
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