MSL3 and PAF1

Data Source:
BioGRID (pull down)

		MSL3	PAF1
Description		MSL complex subunit 3	PAF1 homolog, Paf1/RNA polymerase II complex component
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GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm NuA4 Histone Acetyltransferase Complex MSL Complex	Nucleoplasm Cytoplasm Membrane Cdc73/Paf1 Complex Cell Junction Transcriptionally Active Chromatin
	Molecular Function	DNA Binding Protein Binding Methylated Histone Binding Histone Acetyltransferase Activity (H4-K16 Specific)	RNA Polymerase II Complex Binding Chromatin Binding Protein Binding
	Biological Process	Chromatin Silencing Regulation Of Transcription, DNA-templated Histone Acetylation Histone Deacetylation Histone H4 Acetylation Histone H2A Acetylation Histone H4-K16 Acetylation	Negative Regulation Of Transcription By RNA Polymerase II Endodermal Cell Fate Commitment Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter MRNA Polyadenylation Histone Monoubiquitination Wnt Signaling Pathway Protein Ubiquitination Nucleosome Positioning Stem Cell Population Maintenance Positive Regulation Of Histone Methylation Positive Regulation Of MRNA 3'-end Processing Histone H2B Ubiquitination Protein Localization To Nucleus Negative Regulation Of Myeloid Cell Differentiation Cellular Response To Lipopolysaccharide Positive Regulation Of Cell Cycle G1/S Phase Transition
Pathways		HATs acetylate histones	Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS
Interacting Genes		8 interacting genes: APP CDK6 H3-4 H3C1 H4-16 H4C1 KAT8 PAF1	17 interacting genes: ENO1 ERCC6 FXR2 H1-2 H3C1 HSPB1 KAT8 KMT2A LEO1 MLLT1 MSL1 MSL2 MSL3 RNF20 SUMO2 TCEA1 TULP3
Entrez ID		10943	54623
HPRD ID		05344	10140
Ensembl ID		ENSG00000005302	ENSG00000006712
Uniprot IDs		Q8N5Y2	A0A024R0H6 Q8N7H5
PDB IDs		2Y0N 3OA6 3OB9	4M6T 5ZYQ 6GMH 6TED
Enriched GO Terms of Interacting Partners?
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