TXNL4A and PQBP1

Data Source:
HPRD (in vivo, two hybrid)

		TXNL4A	PQBP1
Description		thioredoxin like 4A	polyglutamine binding protein 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Cytosol Nuclear Membrane U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome	Nucleus Nucleoplasm Cytoplasm Cytoplasmic Stress Granule Nuclear Body Nuclear Speck Neuronal Ribonucleoprotein Granule
	Molecular Function	Protein Binding	DNA Binding Double-stranded DNA Binding Transcription Coactivator Activity Protein Binding Ribonucleoprotein Complex Binding
	Biological Process	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Cell Cycle Cell Division	Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Activation Of Innate Immune Response Positive Regulation Of Defense Response To Virus By Host Regulation Of Transcription, DNA-templated Neuron Projection Development Positive Regulation Of Type I Interferon Production Regulation Of RNA Splicing Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Dendrite Morphogenesis Defense Response To Virus Cellular Response To Exogenous DsRNA
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	mRNA Splicing - Major Pathway
Drugs
Diseases			Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS) Non-syndromic X-linked mental retardation
GWAS
Interacting Genes		8 interacting genes: CD2BP2 DDIT4L ERBB3 EXOC5 HNRNPF LZTS2 PQBP1 RHEBL1	24 interacting genes: APBB1 APP AQR ATXN1 CLTB EEF1A1 ERG28 ESR1 GOLGA2 HNRNPH2 LNX1 LRIF1 LZTS2 MAPRE1 MED31 POLR2A POU3F2 RAB8A RCVRN SFTPC TLX3 TXNL4A WBP11 WDR77
Entrez ID		10907	10084
HPRD ID		18252	02354
Ensembl ID		ENSG00000141759	ENSG00000102103
Uniprot IDs		K7ESL1 P83876	A0A0S2Z4V5 O60828
PDB IDs		1PQN 1QGV 1SYX 3JCR 4BWQ 4BWS 4CDO 5O9Z 6AH0 6AHD 6QW6 6QX9	4BWQ 4BWS 4CDO
Enriched GO Terms of Interacting Partners?
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