DHRS4 and PEX5

Data Source:
BioGRID (affinity chromatography technology, unspecified method, affinity chromatography technology)

		DHRS4	PEX5
Description		dehydrogenase/reductase 4	peroxisomal biogenesis factor 5
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GO Annotations	Cellular Component	Nucleus Mitochondrion Peroxisome Peroxisomal Membrane Peroxisomal Matrix Endoplasmic Reticulum Membrane Cytosol	Cytoplasm Peroxisome Peroxisomal Membrane Golgi Apparatus Cytosol Membrane Protein-containing Complex
	Molecular Function	3-keto Sterol Reductase Activity Carbonyl Reductase (NADPH) Activity Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor Alcohol Dehydrogenase [NAD(P)+] Activity Identical Protein Binding	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Enzyme Binding Small GTPase Binding Peroxisome Membrane Targeting Sequence Binding Protein N-terminus Binding Protein Sequestering Activity
	Biological Process	Alcohol Metabolic Process Protein Targeting To Peroxisome Steroid Metabolic Process Cellular Ketone Metabolic Process	Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Protein Ubiquitination Negative Regulation Of Protein-containing Complex Assembly Protein Import Into Peroxisome Membrane
Pathways		RA biosynthesis pathway Peroxisomal protein import Peroxisomal protein import	Pexophagy
Drugs		Vitamin A
Diseases			Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		Bipolar disorder ( 20351715)	IgG glycosylation ( 23382691) Night sleep phenotypes ( 27126917) Refractive error ( 32231278)
Interacting Genes		1 interacting genes: PEX5	76 interacting genes: ACD ACOT2 ACOT4 ACOT8 ACOX2 ACOX3 AGXT AMACR ANKRD50 ATM BAAT BRCA1 CAPRIN2 CCDC14 CROT DAO DDO DECR2 DHRS4 ECI2 EP400P1 EPHX2 GDPD5 GLMN GNPAT GSTK1 HACL1 HAO1 HAO2 HMGCL HNRNPH1 HOXA7 HSPA1A IDE IDH1 LDHB LONP2 MKRN3 MLYCD MPV17 NOS2 NUDT19 NUDT3 NUDT7 PAOX PDZK1 PEX1 PEX10 PEX12 PEX13 PEX14 PEX26 PEX6 PEX7 PIPOX POT1 PRDX5 PRR13 PSAP RPL14 S100A6 SCARB1 SCP2 SCRN2 SIRT3 SLC27A2 SNUPN SSTR5 TIMMDC1 TINF2 TM6SF1 TOMM7 USP2 USP9X ZFAND3 ZNF772
Entrez ID		10901	5830
HPRD ID		07484	02684
Ensembl ID		ENSG00000157326	ENSG00000139197
Uniprot IDs		Q9BTZ2	A0A0S2Z480 A0A0S2Z4F3 A0A0S2Z4H1 B4DR50 B4E0T2 P50542
PDB IDs		3O4R	1FCH 2C0L 2C0M 2J9Q 2W84 3R9A 4BXU 4KXK 4KYO
Enriched GO Terms of Interacting Partners?
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