RPP40 and RPP38

Data Source:
HPRD (in vivo)

		RPP40	RPP38
Description		ribonuclease P/MRP subunit p40	ribonuclease P/MRP subunit p38
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GO Annotations	Cellular Component	Ribonuclease MRP Complex Nucleus Nucleoplasm Nucleolar Ribonuclease P Complex Multimeric Ribonuclease P Complex	Fibrillar Center Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex
	Molecular Function	Ribonuclease MRP Activity Ribonuclease P Activity Ribonuclease P RNA Binding	Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) TRNA 5'-leader Removal Endonucleolytic Cleavage Involved In TRNA Processing	TRNA 5'-leader Removal RRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol	tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Clozapine-induced agranulocytosis ( 25187353) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		8 interacting genes: MEOX2 POP1 POP7 PTEN RPP14 RPP21 RPP30 RPP38	9 interacting genes: POP1 POP4 POP7 PTEN RPP14 RPP21 RPP25 RPP30 RPP40
Entrez ID		10799	10557
HPRD ID		09361	09360
Ensembl ID		ENSG00000124787	ENSG00000152464
Uniprot IDs		A0A087X1N3 O75818	P78345
PDB IDs		6AHR 6AHU 6AHV	6AHR 6AHU
Enriched GO Terms of Interacting Partners?
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