CELF2 and APOBEC1

Data Source:
HPRD (in vivo, in vitro)

		CELF2	APOBEC1
Description		CUGBP Elav-like family member 2	apolipoprotein B mRNA editing enzyme catalytic subunit 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Intracellular Membrane-bounded Organelle Flemming Body Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Pre-mRNA Binding	RNA Binding MRNA Binding Cytidine Deaminase Activity Cytosine Deaminase Activity Protein Binding Enzyme Activator Activity Zinc Ion Binding Protein Domain Specific Binding Ribonucleoprotein Complex Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splice Site Selection RNA Processing Regulation Of Heart Contraction	RNA Processing MRNA Processing Lipid Metabolic Process Response To Osmotic Stress Cytidine Deamination Response To Zinc Ion Cytidine To Uridine Editing MRNA Modification Cellular Response To Insulin Stimulus Response To Drug Response To Ethanol Regulation Of Catalytic Activity Response To Calcium Ion Defense Response To Virus DNA Cytosine Deamination DNA Demethylation Negative Regulation Of DNA Methylation-dependent Heterochromatin Assembly Positive Regulation Of MRNA Modification
Pathways			mRNA Editing: C to U Conversion Formation of the Editosome
Drugs			Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Adverse response to drug ( 30420678) Allergic rhinitis ( 30013184) Asthma ( 29273806) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Body size at age 10 ( 32376654) Breastfeeding duration ( 25475840) Chronic kidney disease ( 31015462) General risk tolerance (MTAG) ( 30643258) Glycemic traits (pleiotropy) ( 31021400) Liver enzyme levels (alanine transaminase) ( 24124411) Liver enzyme levels (aspartate transaminase) ( 24124411) Mean platelet volume ( 32888494) Motion sickness ( 25628336) Obesity-related traits ( 23251661) Offspring birth weight ( 31043758) Pulse pressure ( 30224653) Response to lamotrigine in genetic generalized epilepsy ( 32308125) Urinary albumin-to-creatinine ratio ( 26631737)	Body mass index ( 28552196) Creatine kinase levels ( 29403010) HDL cholesterol levels ( 28334899)
Interacting Genes		21 interacting genes: A1CF APOBEC1 APP ELAVL1 MIR140 MIR155 MIR18B MIR199A1 MIR19A MIR19B1 MIR205 MIR21 MIR29C MIR34B MIR363 MIR7-1 MIR9-2 MIRLET7I PCBP1 PTGS2 TRAF3	16 interacting genes: A1CF APOBEC2 BAG4 CDK6 CELF2 DNAJB11 DND1 HNRNPF HNRNPK KPNA2 KRTAP19-5 KRTAP6-1 KRTAP6-2 NOTO SYNCRIP UFSP2
Entrez ID		10659	339
HPRD ID		03964	02531
Ensembl ID		ENSG00000048740	ENSG00000111701
Uniprot IDs		A0A0J9YX66 A0A0J9YXJ0 A0A1B0GU44 A0A1B0GUN8 B4DDE7 B4DIB6 B4DT00 B4DZ01 E9PC62 O95319	P41238
PDB IDs		2MY7 2MY8 4LJM 4LMZ 4TLQ 5M8I
Enriched GO Terms of Interacting Partners?
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