APOBEC1 and APOBEC2

Data Source:
HPRD (in vitro)

		APOBEC1	APOBEC2
Description		apolipoprotein B mRNA editing enzyme catalytic subunit 1	apolipoprotein B mRNA editing enzyme catalytic subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Cytoplasm
	Molecular Function	RNA Binding MRNA Binding Cytidine Deaminase Activity Cytosine Deaminase Activity Protein Binding Enzyme Activator Activity Zinc Ion Binding Protein Domain Specific Binding Ribonucleoprotein Complex Binding	RNA Binding Cytidine Deaminase Activity Identical Protein Binding Metal Ion Binding
	Biological Process	RNA Processing MRNA Processing Lipid Metabolic Process Response To Osmotic Stress Cytidine Deamination Response To Zinc Ion Cytidine To Uridine Editing MRNA Modification Cellular Response To Insulin Stimulus Response To Drug Response To Ethanol Regulation Of Catalytic Activity Response To Calcium Ion Defense Response To Virus DNA Cytosine Deamination DNA Demethylation Negative Regulation Of DNA Methylation-dependent Heterochromatin Assembly Positive Regulation Of MRNA Modification	MRNA Processing Cytidine Deamination Cytidine To Uridine Editing MRNA Modification DNA Demethylation
Pathways		mRNA Editing: C to U Conversion Formation of the Editosome	mRNA Editing: C to U Conversion Formation of the Editosome
Drugs		Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Body mass index ( 28552196) Creatine kinase levels ( 29403010) HDL cholesterol levels ( 28334899)
Interacting Genes		16 interacting genes: A1CF APOBEC2 BAG4 CDK6 CELF2 DNAJB11 DND1 HNRNPF HNRNPK KPNA2 KRTAP19-5 KRTAP6-1 KRTAP6-2 NOTO SYNCRIP UFSP2	1 interacting genes: APOBEC1
Entrez ID		339	10930
HPRD ID		02531	07268
Ensembl ID		ENSG00000111701	ENSG00000124701
Uniprot IDs		P41238	Q9Y235
PDB IDs			2NYT
Enriched GO Terms of Interacting Partners?
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