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IGF2BP3 and MIR15B
Data Source:
BioGRID
(unspecified method)
IGF2BP3
MIR15B
Description
insulin like growth factor 2 mRNA binding protein 3
microRNA 15b
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Extracellular Space
Extracellular Vesicle
Molecular Function
RNA Binding
MRNA Binding
MRNA 3'-UTR Binding
Protein Binding
Translation Regulator Activity
MRNA 5'-UTR Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
Regulation Of Cytokine Production
Translation
Nervous System Development
Anatomical Structure Morphogenesis
Regulation Of Gene Expression
Negative Regulation Of Translation
Regulation Of MRNA Stability
MRNA Transport
Regulation Of RNA Metabolic Process
Branching Involved In Blood Vessel Morphogenesis
Cardiac Muscle Hypertrophy
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Angiogenesis
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Positive Regulation Of Apoptotic Process
Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Neuron Apoptotic Process
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of Translation
Negative Regulation Of Mitotic Cell Cycle
Negative Regulation Of Inflammatory Response
Negative Regulation Of Wound Healing
Negative Regulation Of Trophoblast Cell Migration
Negative Regulation Of NIK/NF-kappaB Signaling
Negative Regulation Of Amyloid-beta Formation
Negative Regulation Of Amyloid Precursor Protein Catabolic Process
Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation
Positive Regulation Of Connective Tissue Replacement
Negative Regulation Of Vascular Endothelial Cell Proliferation
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA
Drugs
Diseases
GWAS
Birth weight (
31043758
27680694
)
Height (
28552196
20881960
25282103
23563607
)
Hip circumference adjusted for BMI (
25673412
)
Infant length (
25281659
)
Offspring birth weight (
31043758
)
Personality dimensions (
23903073
)
Type 2 diabetes (
30297969
)
White blood cell count (
32888494
)
Bipolar disorder (
31043756
)
Malaria (
31844061
)
Interacting Genes
76 interacting genes:
DUX4
MEOX2
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
PCBP1
PIH1D2
102 interacting genes:
ADARB1
AIMP1
APOBEC3B
AQR
ATXN2L
C1QBP
CELF1
CPSF1
CSTF3
DARS1
DCP1A
DCP1B
DCP2
DDX1
DDX21
DDX3X
DDX3Y
DHX36
DHX37
EDC3
EDC4
EIF2AK2
EPRS1
ERAL1
ESRP1
FAM98A
FIP1L1
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LRPPRC
MARS1
MATR3
MSI1
MSI2
NOL6
NONO
NUDT21
NUFIP2
PATL1
PDCD11
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PUM1
PURA
QARS1
RARS1
RBFOX2
RBM12B
RBM14
RBM4
RBM45
RBMS2
RTCA
RTCB
SF3A1
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SUGP2
SYMPK
SYNCRIP
TAF15
TENT2
TRA2A
TRA2B
U2SURP
UPF1
USP36
UTP20
YBX1
YBX2
YBX3
ZFR
ZNF346
Entrez ID
10643
406949
HPRD ID
16306
Ensembl ID
ENSG00000136231
ENSG00000207779
Uniprot IDs
O00425
PDB IDs
2E44
6FQ1
6FQR
6GQE
6GX6
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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