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SORBS1 and RPL4
Data Source:
BioGRID
(two hybrid)
SORBS1
RPL4
Description
sorbin and SH3 domain containing 1
ribosomal protein L4
Image
GO Annotations
Cellular Component
Stress Fiber
Nucleus
Centrosome
Cytosol
Plasma Membrane
Adherens Junction
Zonula Adherens
Focal Adhesion
Nuclear Matrix
Cell-substrate Junction
Membrane Raft
Nucleus
Nucleolus
Cytoplasm
Rough Endoplasmic Reticulum
Cytosol
Focal Adhesion
Membrane
Cytosolic Large Ribosomal Subunit
Extracellular Exosome
Ribonucleoprotein Complex
Molecular Function
Actin Binding
Insulin Receptor Binding
Protein Binding
Cytoskeletal Protein Binding
Signaling Receptor Complex Adaptor Activity
RNA Binding
Structural Constituent Of Ribosome
Protein Binding
Biological Process
Muscle Contraction
Cell-matrix Adhesion
Insulin Receptor Signaling Pathway
Cellular Response To Insulin Stimulus
Stress Fiber Assembly
Positive Regulation Of Glycogen Biosynthetic Process
Positive Regulation Of Glucose Import
Positive Regulation Of Insulin Receptor Signaling Pathway
Positive Regulation Of Lipid Biosynthetic Process
Focal Adhesion Assembly
Positive Regulation Of Protein Localization To Plasma Membrane
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Translation
Translational Initiation
SRP-dependent Cotranslational Protein Targeting To Membrane
Viral Transcription
Pathways
Smooth Muscle Contraction
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Artenimol
Diseases
GWAS
Diabetic nephropathy in type 1 diabetes (
25476525
)
Estimated glomerular filtration rate (
31152163
)
Hematocrit (
32888494
)
Mean platelet volume (
32888494
)
Obesity-related traits (
23251661
)
PR interval (
30046033
32439900
)
Red blood cell count (
32888494
)
Staphylococcus aureus nasal carriage (persistent) (
26569114
)
Suicide risk (
21041247
)
Interacting Genes
27 interacting genes:
ABI1
ABL1
ACTA1
ADAM15
AFDN
CBL
CDK6
EFNB1
FLOT1
INPPL1
INSM1
INSR
KHDRBS1
MAP4K3
PAK2
PGR
PILRA
PTK2
PXN
RPL4
RTN4IP1
SEMA6A
SH2B2
SLC10A3
SRC
TENM1
VCL
15 interacting genes:
APBB1
APOE
DUX4
DUX4L9
IL32
MAP3K14
MDM2
MYB
NDRG1
PBX2
PIN1
PRPF40A
SORBS1
SUMO2
TNPO2
Entrez ID
10580
6124
HPRD ID
05587
01607
Ensembl ID
ENSG00000095637
ENSG00000174444
Uniprot IDs
B4DTX5
Q9BX66
P36578
PDB IDs
2DL3
2ECZ
2LJ0
2LJ1
2MOX
2O2W
2O31
2O9S
2O9V
4LN2
4LNP
4UG0
4V6X
5A8L
5AJ0
5LKS
5T2C
6EK0
6IP5
6IP6
6IP8
6LQM
6LSR
6LSS
6LU8
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
6W6L
6XA1
6Y0G
6Y2L
6Y57
6Y6X
6Z6L
6Z6M
6Z6N
6ZM7
6ZME
6ZMI
6ZMO
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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