CCT2 and NPSR1

Data Source:
BioGRID (two hybrid)

		CCT2	NPSR1
Description		chaperonin containing TCP1 subunit 2	neuropeptide S receptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Zona Pellucida Receptor Complex Extracellular Region Cytosol Chaperonin-containing T-complex Microtubule Azurophil Granule Lumen Cell Body Extracellular Exosome	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Protein Folding Chaperone Unfolded Protein Binding	Vasopressin Receptor Activity Neuropeptide Receptor Activity
	Biological Process	Protein Folding Binding Of Sperm To Zona Pellucida Positive Regulation Of Telomere Maintenance Via Telomerase Neutrophil Degranulation Protein Stabilization Chaperone Mediated Protein Folding Independent Of Cofactor Chaperone-mediated Protein Complex Assembly Positive Regulation Of Telomerase Activity ScaRNA Localization To Cajal Body Toxin Transport Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body	G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis BBSome-mediated cargo-targeting to cilium Neutrophil degranulation Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	Peptide ligand-binding receptors G alpha (q) signalling events G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs			Halothane
Diseases
GWAS		Height ( 18391951) Logical memory (delayed recall) in normal cognition ( 29274321) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532)	Anti-chlamydia trachomatis IgG seropositivity ( 29967566) Asthma ( 29273806) Leisure-time exercise behaviour ( 30102679) Plasma anti-thyroglobulin levels ( 29678681) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		23 interacting genes: ACTA1 ACTB CCT4 EEF2 ERLIN2 ESR1 FCHSD2 HSP90AB1 HSP90B1 LINC01554 NPSR1 PRPF40A PSMC6 PSMD2 PTEN RPS3 SUMO2 SUMO4 TUBA1B VAV2 VRK2 YWHAG ZNRD2	16 interacting genes: ATP5F1A CCT2 ENTPD6 GABARAPL2 HLA-C IPO13 MFSD10 PGM2L1 PMPCB PRR36 RABGGTB SLC3A2 SLC41A3 TERF2IP TMED10 TMEM101
Entrez ID		10576	387129
HPRD ID		06895	10547
Ensembl ID		ENSG00000166226	ENSG00000187258
Uniprot IDs		P78371 V9HW96	A0A090N8Z1 Q6W5P4
PDB IDs		6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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