SIVA1 and ZNF446

Data Source:
BioGRID (two hybrid)

		SIVA1	ZNF446
Description		SIVA1 apoptosis inducing factor	zinc finger protein 446
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Chromatin Extracellular Space Nucleus
	Molecular Function	Virus Receptor Activity Tumor Necrosis Factor Receptor Binding CD27 Receptor Binding Protein Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Viral Entry Into Host Cell Extrinsic Apoptotic Signaling Pathway	Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs		Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Endometrial cancer ( 27135401) Endometrial endometrioid carcinoma ( 27135401) Thyroid stimulating hormone levels ( 32769997)	Obesity-related traits ( 23251661) Uric acid clearance ( 28095793)
Interacting Genes		30 interacting genes: ABL2 APP AQP1 BCL2L1 BEX3 C2orf68 CATSPER1 CD27 CD4 CDKN2A CREB5 HOXA1 ING3 KRTAP26-1 MEFV NEDD4 NEDD4L NTAQ1 PCNA PM20D2 POLR2M PXMP2 RAD18 RHOU SSBP3 TCAP TFAP2D TNFRSF4 UBE2D1 ZNF446	60 interacting genes: ACTN2 ANKRD1 CCNK COPS2 CYSRT1 DGCR6 DGCR6L EHMT2 EVI5 FHL5 FRMD8 FRS3 GOLGA6L9 INCA1 KIFC3 KRT31 KRT34 KRT35 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP3-1 LNX1 LZTS2 MAGOHB MDFI NBPF19 NOTCH2NLA PGBD1 PIN1 REL SCAND1 SIVA1 SUFU TAX1BP1 TRIM27 UBE2I UBE3A ZKSCAN4 ZKSCAN7 ZNF165 ZNF18 ZNF232 ZNF24 ZNF263 ZNF396 ZNF397 ZNF483 ZNF496 ZSCAN12 ZSCAN16 ZSCAN18 ZSCAN21 ZSCAN22 ZSCAN23 ZSCAN29 ZSCAN30 ZSCAN32 ZSCAN9
Entrez ID		10572	55663
HPRD ID		16124	07934
Ensembl ID		ENSG00000184990	ENSG00000083838
Uniprot IDs		O15304	Q8NDK2 Q9NWS9 Q9UFF2
PDB IDs
Enriched GO Terms of Interacting Partners?
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