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ARFGEF1 and FKBP2
Data Source:
HPRD
(in vitro, in vivo, two hybrid)
ARFGEF1
FKBP2
Description
ADP ribosylation factor guanine nucleotide exchange factor 1
FKBP prolyl isomerase 2
Image
GO Annotations
Cellular Component
Golgi Membrane
Nucleoplasm
Nucleolus
Golgi Apparatus
Trans-Golgi Network
Cytosol
Nuclear Matrix
Small Nuclear Ribonucleoprotein Complex
Perinuclear Region Of Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Molecular Function
Guanyl-nucleotide Exchange Factor Activity
GTPase Activator Activity
Protein Binding
Myosin Binding
Protein Kinase A Regulatory Subunit Binding
Peptidyl-prolyl Cis-trans Isomerase Activity
Protein Binding
FK506 Binding
Biological Process
Exocytosis
Golgi Organization
Endomembrane System Organization
Protein Transport
Negative Regulation Of Actin Filament Polymerization
Neuron Projection Development
Regulation Of ARF Protein Signal Transduction
Negative Regulation Of GTPase Activity
Positive Regulation Of GTPase Activity
Positive Regulation Of Protein Kinase B Signaling
Positive Regulation Of Protein Glycosylation In Golgi
Positive Regulation Of Wound Healing
Regulation Of Establishment Of Cell Polarity
Protein Peptidyl-prolyl Isomerization
Pathways
Drugs
Diseases
GWAS
Chronic central serous retinopathy (
30073298
)
Hearing function (
25060954
)
Hip circumference adjusted for BMI (
28552196
)
Crohn's disease (
28067908
)
Fruit consumption (
32066663
)
Interacting Genes
5 interacting genes:
ARFGEF2
CTNNB1
DPY30
FKBP2
MYO9B
14 interacting genes:
ARFGEF1
BAG6
BARD1
C1QC
EPB41
EPB41L2
MAPK3
RAB3C
RAB6A
RAP2A
UBQLN1
UBQLN2
UBQLN4
VAMP2
Entrez ID
10565
2286
HPRD ID
09163
01742
Ensembl ID
ENSG00000066777
ENSG00000173486
Uniprot IDs
A0A024R7X0
Q9Y6D6
P26885
Q53XJ5
PDB IDs
3LTL
5EE5
5J5C
2PBC
4NNR
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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