RPP30 and MAST1

Data Source:
BioGRID (two hybrid)

		RPP30	MAST1
Description		ribonuclease P/MRP subunit p30	microtubule associated serine/threonine kinase 1
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GO Annotations	Cellular Component	Ribonuclease MRP Complex Nucleus Nucleoplasm Nucleolar Ribonuclease P Complex Multimeric Ribonuclease P Complex	Cytoplasm Cytoskeleton Plasma Membrane Axon Dendrite Neuron Projection Neuronal Cell Body
	Molecular Function	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Microtubule Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	TRNA 5'-leader Removal RRNA Processing TRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Protein Phosphorylation Cytoskeleton Organization Brain Development Peptidyl-serine Phosphorylation Intracellular Signal Transduction
Pathways		tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs			Fostamatinib
Diseases
GWAS		Economic and political preferences (time) ( 22566634) Metabolite levels ( 23823483)	High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) Intelligence (MTAG) ( 29326435) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Red blood cell count ( 29403010) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		11 interacting genes: HMG20A MAST1 POP1 POP4 POP5 PTEN RNF32 RPP14 RPP21 RPP38 RPP40	40 interacting genes: A2M AP1M2 APOE APP BLMH CDK5 CYP2C8 CYP2C9 DNAJB1 ECSIT EGFR ELAVL3 EXOC6 EXOSC1 FBXL12 FBXW4 GCDH HSP90AB1 IFIT3 IFIT5 LONP1 LOXL4 NOS3 OGA PAXIP1 PRAM1 PRDX2 PSEN2 PTEN RAB3A RAB3D RAD23A RNF32 RNLS RPP30 RPS6KA1 SNTA1 SNTB2 STAMBPL1 UBE2D3
Entrez ID		10556	22983
HPRD ID		09359	17469
Ensembl ID		ENSG00000148688	ENSG00000105613
Uniprot IDs		P78346	Q9Y2H9
PDB IDs		6AHR 6AHU	2M9X 3PS4
Enriched GO Terms of Interacting Partners?
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