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HTATIP2 and RAB5A
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology, protein complementation assay)
HTATIP2
RAB5A
Description
HIV-1 Tat interactive protein 2
RAB5A, member RAS oncogene family
Image
GO Annotations
Cellular Component
Nucleus
Nuclear Envelope
Cytoplasm
Cytosol
Membrane
Ruffle
Nucleoplasm
Cytoplasm
Endosome
Early Endosome
Cytosol
Plasma Membrane
Synaptic Vesicle
Endosome Membrane
Endomembrane System
Actin Cytoskeleton
Endocytic Vesicle
Axon
Dendrite
Clathrin-coated Vesicle Membrane
Phagocytic Vesicle Membrane
Early Endosome Membrane
Early Phagosome
Somatodendritic Compartment
Melanosome
Neuronal Cell Body
Terminal Bouton
Intracellular Membrane-bounded Organelle
Axon Terminus
Membrane Raft
Phagocytic Vesicle
Extracellular Exosome
Cytoplasmic Side Of Early Endosome Membrane
Postsynaptic Early Endosome
Anchored Component Of Synaptic Vesicle Membrane
Molecular Function
Transcription Coactivator Activity
Protein Serine/threonine Kinase Activity
Protein Binding
Oxidoreductase Activity
GTPase Activity
Protein Binding
GTP Binding
GDP Binding
Biological Process
Angiogenesis
Regulation Of Transcription By RNA Polymerase II
Apoptotic Process
Viral Process
Cell Differentiation
Negative Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Regulation Of Angiogenesis
Positive Regulation Of Transcription By RNA Polymerase II
Protein Autophosphorylation
Import Into Nucleus
Phosphatidylinositol Biosynthetic Process
Intracellular Protein Transport
Endocytosis
Phagocytosis
Blood Coagulation
Regulation Of Endocytosis
Synaptic Vesicle Recycling
Viral RNA Genome Replication
Post-translational Protein Modification
Early Endosome To Late Endosome Transport
Positive Regulation Of Exocytosis
Regulation Of Long-term Neuronal Synaptic Plasticity
Regulation Of Endosome Size
Regulation Of Filopodium Assembly
Membrane Organization
Amyloid-beta Clearance By Transcytosis
Receptor Internalization Involved In Canonical Wnt Signaling Pathway
Regulation Of Synaptic Vesicle Exocytosis
Regulation Of Autophagosome Assembly
Pathways
Synthesis of PIPs at the plasma membrane
TBC/RABGAPs
Clathrin-mediated endocytosis
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs
Prevention of phagosomal-lysosomal fusion
Factors involved in megakaryocyte development and platelet production
Drugs
Polyethylene glycol 400
L-methionine (S)-S-oxide
Guanosine-5'-Triphosphate
Guanosine-5'-Diphosphate
Diseases
GWAS
Fractional shortening (
29403010
)
Obesity-related traits (
23251661
)
Response to inhaled glucocorticoid treatment in asthma (change in FEV1) (
25601762
)
Heel bone mineral density (
30598549
)
Iris color (L* coordinate) (
30895295
)
Interacting Genes
25 interacting genes:
ABHD4
ACSL4
AQP6
ASF1A
EHHADH
ETS1
FAM209A
FITM2
GET1
HDAC6
HSD17B11
JAGN1
JPH1
MIEF1
MTIF3
NCOA5
PITPNC1
PLIN2
RAB5A
REEP4
RETREG3
SH3GLB1
SLC10A6
TMEM115
TMX2
35 interacting genes:
AGTR1
ALS2CL
ANKFY1
APPL1
APPL2
CHML
EEA1
GDI2
GRIK4
HTATIP2
ITSN1
NME2
OCRL
RAB37
RABAC1
RABEP1
RABEP2
RABGGTB
RASA1
RBSN
RIN1
RIN2
RIN3
RIT2
RUFY1
SDCBP
SGSM3
STX4
TBC1D15
TBC1D17
TBC1D3C
TBC1D3F
TRIM14
TSC2
USP6NL
Entrez ID
10553
5868
HPRD ID
09288
01542
Ensembl ID
ENSG00000109854
ENSG00000144566
Uniprot IDs
Q9BUP3
A0A024R2K1
P20339
PDB IDs
2BKA
1N6H
1N6I
1N6K
1N6L
1N6N
1N6O
1N6P
1N6R
1R2Q
1TU3
1TU4
3MJH
4Q9U
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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