IPO7 and LIMS1

Data Source:
BioGRID (two hybrid)

		IPO7	LIMS1
Description		importin 7	LIM zinc finger domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Pore Nucleoplasm Cytosol Membrane	Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Focal Adhesion Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Transporter Activity Protein Binding GTPase Regulator Activity Small GTPase Binding Histone Binding SMAD Binding	Protein Binding Zinc Ion Binding Protein Kinase Binding Protein-containing Complex Binding
	Biological Process	Protein Import Into Nucleus Signal Transduction Viral Process Innate Immune Response Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity	Epithelial To Mesenchymal Transition Cell Aging Positive Regulation Of Gene Expression Positive Regulation Of Cell-substrate Adhesion Tumor Necrosis Factor-mediated Signaling Pathway Cell Junction Assembly Positive Regulation Of GTPase Activity Establishment Of Protein Localization Cell-cell Junction Organization Negative Regulation Of Transcription, DNA-templated Regulation Of Epithelial Cell Proliferation Positive Regulation Of Focal Adhesion Assembly Cellular Response To Transforming Growth Factor Beta Stimulus Cell-cell Adhesion Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways			Cell-extracellular matrix interactions Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Drugs
Diseases
GWAS		Interleukin-10 levels ( 22205395)	Apolipoprotein B levels ( 32203549) Beard thickness ( 26926045) Birth weight ( 31043758) Excessive hairiness ( 29895819) Eyebrow thickness ( 26926045) Immature fraction of reticulocytes ( 32888494) LDL cholesterol ( 30275531) LDL cholesterol levels ( 32203549) Monobrow thickness ( 26926045) Scalp hair shape ( 26926045)
Interacting Genes		11 interacting genes: AKTIP H1-0 KPNB1 LIMS1 LINC01554 PTEN RAN RPL23A RPL5 RPS7 SRP19	47 interacting genes: ADAMTS9 ATXN10 CATSPER1 CCN2 COL8A1 CSRP3 CWF19L2 DAPK1 EHMT2 FAM90A1 FERMT2 FERMT3 FMR1 GEM ILK INO80B IPO7 KPRP LMO3 LPXN MBIP MYO15B NCK2 NEB OSR2 PARVA PEG3 PLCE1 RAD51D RBBP8 RSU1 SCNM1 SMURF1 TBC1D22B TCEA2 TGFBR1 TMSB4X TRIO TTN USP11 ZIM2 ZMYM4 ZNF160 ZNF410 ZNF417 ZNF564 ZNF587
Entrez ID		10527	3987
HPRD ID		09280	03978
Ensembl ID		ENSG00000205339	ENSG00000169756
Uniprot IDs		B3KNG9 O95373	P48059
PDB IDs			1G47 1NYP 1U5S 2COR 2D8X 2KBX 3F6Q 4HI8 4HI9 6MIF
Enriched GO Terms of Interacting Partners?
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