CLEC10A and ZDHHC15

Data Source:
BioGRID (two hybrid)

		CLEC10A	ZDHHC15
Description		C-type lectin domain containing 10A	zinc finger DHHC-type palmitoyltransferase 15
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Postsynaptic Density Integral Component Of Golgi Membrane Postsynapse
	Molecular Function	Protein Binding Carbohydrate Binding	Protein Binding Zinc Ion Binding Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity
	Biological Process	Stimulatory C-type Lectin Receptor Signaling Pathway Adaptive Immune Response Endocytosis Innate Immune Response	Protein Targeting To Membrane Synaptic Vesicle Maturation Protein Phosphopantetheinylation Peptidyl-L-cysteine S-palmitoylation Protein Palmitoylation Regulation Of Dendritic Spine Morphogenesis Protein Localization To Postsynapse Protein Localization To Membrane Protein Targeting To Golgi Apparatus Positive Regulation Of Dendrite Development
Pathways		Dectin-2 family
Drugs
Diseases			Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
GWAS		Carotid intima media thickness x smoking interaction ( 32117412) GIP levels in response to oral glucose tolerance test (120 minutes) ( 29093273) Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		24 interacting genes: ACSF2 ADIPOQ APOD BET1 C3orf52 CLN6 FMO3 FXYD6 GIMAP1 MALL NAPB PEX16 PRAF2 SEC22A SLC38A7 SMCO4 TMEM218 TNF TRARG1 TSPO UNC50 VSTM1 ZDHHC15 ZFPL1	48 interacting genes: ADCYAP1R1 ARL13B BNIP3 C14orf180 CD79A CELA2B CERCAM CLEC10A CLRN1 CREB3L1 CYB5R3 DHRSX ERGIC3 FAM241B GIMAP1 GOLGA7B GPR152 LEMD1 LEPROTL1 LHFPL5 LMNA LSMEM1 MCEMP1 MTIF3 ORMDL1 ORMDL2 PEX16 PLLP PRAF2 PVR RUSF1 SLC10A6 SMIM1 SNORC STX3 TBXA2R TMEFF2 TMEM120B TMEM128 TMEM14C TMEM222 TMEM42 TMEM52B TNFRSF10B TSNARE1 TUFM VAPB YIPF4
Entrez ID		10462	158866
HPRD ID		12076	06758
Ensembl ID		ENSG00000132514	ENSG00000102383
Uniprot IDs		J3KR22 Q8IUN9	B3KY34 Q96MV8
PDB IDs		6PUV 6PY1
Enriched GO Terms of Interacting Partners?
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