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TMEM147 and TACR1
Data Source:
BioGRID
(two hybrid)
TMEM147
TACR1
Description
transmembrane protein 147
tachykinin receptor 1
Image
GO Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Plasma Membrane
Integral Component Of Membrane
Protein-containing Complex
Plasma Membrane
Integral Component Of Plasma Membrane
Sperm Flagellum
Sperm Head
Sperm Midpiece
Molecular Function
Protein Binding
Tachykinin Receptor Activity
Protein Binding
Substance P Receptor Activity
Biological Process
Inflammatory Response
G Protein-coupled Receptor Signaling Pathway
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Tachykinin Receptor Signaling Pathway
Detection Of Abiotic Stimulus
Response To Pain
Regulation Of Uterine Smooth Muscle Contraction
Positive Regulation Of Flagellated Sperm Motility
Pathways
Tachykinin receptors bind tachykinins
G alpha (q) signalling events
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Drugs
Tramadol
Aprepitant
Ketamine
Vapreotide
AV608
GW 597599
CP-122721
R673
SR 140333
Casopitant
Netupitant
Rolapitant
Vestipitant
Vofopitant
Fosnetupitant
Diseases
GWAS
Brain connectivity (
23471985
)
Chronotype (
30696823
)
Diisocyanate-induced asthma (
25918132
)
Gout (
32238385
)
Nonunion in individuals with fractures (
30680360
)
Pursuit maintenance gain (
29064472
)
Seborrheic dermatitis (
29203360
)
Sexual dimorphism in anthropometric traits (
23754948
)
Weight (
28552196
)
Interacting Genes
54 interacting genes:
ABHD16A
ABI3
CD40
CD79A
CLDN7
CLN8
CLRN1
CREB3L1
CXCR2
DPM3
EBP
EFNA4
ENPP4
F11R
FFAR2
GJA8
GLP1R
GOLM1
GPR101
GPR37L1
GPR42
GPR61
HTR2C
IL3RA
KASH5
LDLRAD1
LEUTX
LHFPL2
MTIF3
MUC1
PACC1
PDCD1LG2
PSCA
PVR
RMDN3
RNF185
SCAMP4
SHISA3
SLC10A1
SLC12A7
SLC13A4
SLC22A1
SLC22A2
SUSD3
SYNE4
TACR1
TEX29
TMEM14B
TMEM237
TMEM248
TMEM252
TMEM42
TMEM52B
TSPAN12
7 interacting genes:
CCDC167
GPRASP1
GRK5
TAC1
TAC3
TAC4
TMEM147
Entrez ID
10430
6869
HPRD ID
17633
01208
Ensembl ID
ENSG00000105677
ENSG00000115353
Uniprot IDs
Q9BVK8
P25103
PDB IDs
6W6L
2KS9
2KSA
2KSB
6E59
6HLL
6HLO
6HLP
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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