CDSN and TGM7

Data Source:
BioGRID (two hybrid)

		CDSN	TGM7
Description		corneodesmosin	transglutaminase 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Extracellular Region Plasma Membrane Cell-cell Junction Desmosome
	Molecular Function	Protein Homodimerization Activity	Protein-glutamine Gamma-glutamyltransferase Activity Protein Binding Metal Ion Binding
	Biological Process	Corneocyte Desquamation Cell Adhesion Epidermis Development Keratinocyte Differentiation Skin Morphogenesis Cornification Cell-cell Adhesion Negative Regulation Of Cornification	Peptide Cross-linking Protein Phosphopantetheinylation
Pathways		Formation of the cornified envelope
Drugs
Diseases		Hypotrichosis simplex of scalp
GWAS		Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Automobile speeding propensity ( 30643258) Blood protein levels ( 28240269) Hematology traits ( 23263863) Hemoglobin levels ( 32327693) HIV-1 control ( 20041166) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Multiple myeloma ( 23955597) Schizophrenia ( 28991256) Takayasu arteritis ( 25604533) Ulcerative colitis ( 28067908) White blood cell count ( 20139978 21738480)
Interacting Genes		37 interacting genes: ASPH ATXN1L BAG6 BANP CCHCR1 CEP55 CSTF2 CSTF2T CTNNA3 DESI1 EIF3F ENKD1 EXOC8 FAM9B HGS HPCAL4 ITPRIPL1 KCNIP3 KLK7 LCN2 NCS1 NELFCD PARVG PLVAP PRKAB2 SGTA SGTB SMARCD1 TGM7 TRIM69 TSGA10 UBQLN1 UBQLN2 UBQLN4 UCHL5 VSNL1 ZDHHC17	20 interacting genes: ARID5A CDSN FRS3 GEM HNRNPF HOXA1 KCTD1 KRT39 LAMTOR3 LNX1 PPP1R32 PRKAB2 QARS1 SDS SPATA18 SPRY1 TNXB TSSK3 UNKL YPEL3
Entrez ID		1041	116179
HPRD ID		03998	09485
Ensembl ID		ENSG00000204539	ENSG00000159495
Uniprot IDs		G8JLG2 Q15517	Q96PF1
PDB IDs
Enriched GO Terms of Interacting Partners?
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