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NDRG1 and RPL4
Data Source:
HPRD
(in vivo)
NDRG1
RPL4
Description
N-myc downstream regulated 1
ribosomal protein L4
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Centrosome
Cytosol
Microtubule
Plasma Membrane
Adherens Junction
Microtubule Cytoskeleton
Perinuclear Region Of Cytoplasm
Recycling Endosome Membrane
Extracellular Exosome
Glutamatergic Synapse
Nucleus
Nucleolus
Cytoplasm
Rough Endoplasmic Reticulum
Cytosol
Focal Adhesion
Membrane
Cytosolic Large Ribosomal Subunit
Extracellular Exosome
Ribonucleoprotein Complex
Molecular Function
Protein Binding
Microtubule Binding
Small GTPase Binding
Gamma-tubulin Binding
Cadherin Binding
RNA Binding
Structural Constituent Of Ribosome
Protein Binding
Biological Process
Signal Transduction
Negative Regulation Of Cell Population Proliferation
Response To Metal Ion
DNA Damage Response, Signal Transduction By P53 Class Mediator
Peripheral Nervous System Myelin Maintenance
Regulation Of Apoptotic Process
Mast Cell Activation
Cellular Response To Hypoxia
Postsynapse Organization
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Translation
Translational Initiation
SRP-dependent Cotranslational Protein Targeting To Membrane
Viral Transcription
Pathways
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Artenimol
Diseases
Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS
Estimated glomerular filtration rate (
31015462
)
Left-handedness (
32989287
)
Nontyphoidal Salmonella bacteraemia (
29523850
)
Post-traumatic stress disorder (asjusted for relatedness) (
23726511
)
Interacting Genes
70 interacting genes:
ACSL3
ACTG1
AP1M2
AP2M1
APOA1
APOA2
ARL4D
ATP1A1
CANX
CDH1
CLTC
CNDP2
COPB2
CTNNB1
DDX1
DDX5
DLST
EEF1G
EEF2
EIF2S3
EIF3E
EWSR1
FASN
GSK3B
HNRNPF
HNRNPH1
HNRNPU
HSD17B4
HSP90AA1
HSPA5
ILF3
KIF5B
LDHA
MAOA
MLH1
MME
MYC
NCL
NR4A1
PABPC1
PHYHIP
PKM
PPP2R2A
PRKACA
PSMC2
PSMC3
PSMD2
RPL24
RPL3
RPL4
RPN2
RPS16
RPS20
RPS26
RPS3
RPS6
RPS8
RTN1
RUVBL2
S100B
SEC23A
SGK1
SHMT2
TAF9
TARS1
TLE3
UPF1
VCP
XRCC5
ZNF155
15 interacting genes:
APBB1
APOE
DUX4
DUX4L9
IL32
MAP3K14
MDM2
MYB
NDRG1
PBX2
PIN1
PRPF40A
SORBS1
SUMO2
TNPO2
Entrez ID
10397
6124
HPRD ID
05586
01607
Ensembl ID
ENSG00000104419
ENSG00000174444
Uniprot IDs
B3KWB2
Q8N959
Q92597
P36578
PDB IDs
4UG0
4V6X
5A8L
5AJ0
5LKS
5T2C
6EK0
6IP5
6IP6
6IP8
6LQM
6LSR
6LSS
6LU8
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
6W6L
6XA1
6Y0G
6Y2L
6Y57
6Y6X
6Z6L
6Z6M
6Z6N
6ZM7
6ZME
6ZMI
6ZMO
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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