RTN3 and UGCG

Data Source:
HPRD (two hybrid)

		RTN3	UGCG
Description		reticulon 3	UDP-glucose ceramide glucosyltransferase
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane Synapse	Golgi Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding Ceramide Glucosyltransferase Activity Dihydroceramide Glucosyltransferase Activity
	Biological Process	Apoptotic Process Viral Process Vesicle-mediated Transport Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Formation Negative Regulation Of Amyloid-beta Formation	Protein Lipidation Glucosylceramide Biosynthetic Process Glycosphingolipid Metabolic Process Epidermis Development Regulation Of Signal Transduction Cell Differentiation Keratinocyte Differentiation Leptin-mediated Signaling Pathway Neuron Development Establishment Of Skin Barrier Intestinal Lipid Absorption Cornified Envelope Assembly
Pathways		Synaptic adhesion-like molecules	Glycosphingolipid metabolism
Drugs			Miglustat Eliglustat
Diseases
GWAS			Benign prostatic hyperplasia ( 30988330) Mean corpuscular hemoglobin ( 32888494) Metabolite levels ( 23823483) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252 28957414)
Interacting Genes		30 interacting genes: AGTR1 CCR2 CCR8 CDIPT CERT1 DRD2 FGFR1 FHIP1B FXR2 GLP1R GPR152 GPR35 LMNA MITD1 NDRG4 PLEKHF2 PLN PPP2R3C PTPN9 RAB33A RMDN2 RTN4 SACM1L SLC30A3 SLC30A8 SNX1 SPOP TERF1 UGCG ZNF391	3 interacting genes: APP RTN1 RTN3
Entrez ID		10313	7357
HPRD ID		18516	04190
Ensembl ID		ENSG00000133318	ENSG00000148154
Uniprot IDs		A0A024R5C4 O95197	A0A024R157 Q16739
PDB IDs		7BRU
Enriched GO Terms of Interacting Partners?
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