UGCG and RTN1

Data Source:
HPRD (two hybrid, in vivo)

		UGCG	RTN1
Description		UDP-glucose ceramide glucosyltransferase	reticulon 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Membrane Integral Component Of Membrane	Golgi Membrane Endoplasmic Reticulum Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Ceramide Glucosyltransferase Activity Dihydroceramide Glucosyltransferase Activity	Protein Binding
	Biological Process	Protein Lipidation Glucosylceramide Biosynthetic Process Glycosphingolipid Metabolic Process Epidermis Development Regulation Of Signal Transduction Cell Differentiation Keratinocyte Differentiation Leptin-mediated Signaling Pathway Neuron Development Establishment Of Skin Barrier Intestinal Lipid Absorption Cornified Envelope Assembly	Negative Regulation Of Amyloid-beta Formation
Pathways		Glycosphingolipid metabolism
Drugs		Miglustat Eliglustat
Diseases
GWAS		Benign prostatic hyperplasia ( 30988330) Mean corpuscular hemoglobin ( 32888494) Metabolite levels ( 23823483) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252 28957414)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Broad depression or schizophrenia ( 30626913) Putamen volume ( 31530798) Schizophrenia ( 30285260)
Interacting Genes		3 interacting genes: APP RTN1 RTN3	15 interacting genes: ADRB2 BCL2L1 CCR4 CHRM5 DRD2 F2RL1 FGFR1 FHIP1B HDAC8 LMNA NDRG1 PLEKHF2 SDCBP SPAST UGCG
Entrez ID		7357	6252
HPRD ID		04190	02921
Ensembl ID		ENSG00000148154	ENSG00000139970
Uniprot IDs		A0A024R157 Q16739	A8K3B9 Q16799
PDB IDs
Enriched GO Terms of Interacting Partners?
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