MARCHF6 and BUD31

Data Source:
BioGRID (two hybrid)

		MARCHF6	BUD31
Description		membrane associated ring-CH-type finger 6	BUD31 homolog
Image		No pdb structure
GO Annotations	Cellular Component	ER Ubiquitin Ligase Complex Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Endoplasmic Reticulum Quality Control Compartment	Chromatin Nucleus Nucleoplasm Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Enzyme Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin Protein Ligase Activity Ubiquitin-specific Protease Binding	Protein Binding Nuclear Receptor Coactivator Activity Nuclear Hormone Receptor Binding
	Biological Process	Proteasomal Protein Catabolic Process Protein Ubiquitination Ubiquitin-dependent ERAD Pathway ERAD Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Endoplasmic Reticulum Mannose Trimming	MRNA Splicing, Via Spliceosome Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Androgen Receptor Activity
Pathways		ER Quality Control Compartment (ERQC)	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Facial emotion recognition (sad faces) ( 28608620) Serum metabolite levels ( 23093944)
Interacting Genes		8 interacting genes: ADGRE2 BUD31 DIO2 MTNR1B RGS2 UBC UBE2D2 UBE2G1	23 interacting genes: ADCY7 APP ATP13A1 BEND5 CCT3 CTNNBL1 ERGIC3 HLA-A HOXA1 HTR5A KRTAP10-3 KRTAP10-7 MARCHF6 MEOX2 MMP24 NPC1 PANX1 PICK1 RELB RNF208 SCAF1 TMEM94 TSPAN7
Entrez ID		10299	8896
HPRD ID		11095	10351
Ensembl ID		ENSG00000145495	ENSG00000106245
Uniprot IDs		O60337	P41223
PDB IDs			4OED 4OH6 4OKB 5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?