Description |
cyclin dependent kinase inhibitor 2A |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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- Adult body size ( 32376654)
- Apolipoprotein B levels ( 32203549)
- Coronary artery disease ( 32469254 24262325 30104761 33020668)
- Coronary artery disease or ischemic stroke ( 24262325)
- Coronary artery disease or large artery stroke ( 24262325)
- Disorders of lipid metabolism ( 30166351)
- HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- Inflammatory skin disease ( 25574825)
- Ischemic stroke ( 29531354)
- LDL cholesterol ( 21347282)
- LDL cholesterol levels ( 32203549 30698716)
- LDL cholesterol levels in current drinkers ( 30698716)
- LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Low density lipoprotein cholesterol levels ( 31969989)
- Medication use (HMG CoA reductase inhibitors) ( 31015401)
- Multiple sclerosis ( 31604244)
- Response to statins (LDL cholesterol change) ( 31969989)
- Stroke ( 29531354)
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Interacting Genes |
168 interacting genes:
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ACLY
ACTB
ACTG1
ACTN4
AHNAK
AKT1
ALDOB
ANAPC15
ANGPTL4
ANKRA2
ANKRD12
AOPEP
ARFIP2
ARNT
ASPRV1
AZIN1
BAAT
BCL2L1
BECN1
CARF
CASC3
CCDC180
CCDC183
CCND2
CCNDBP1
CCNE1
CCNG1
CD44
CDC14B
CDC42
CDC45
CDC5L
CDC6
CDC7
CDK4
CDK6
CDKN2AIP
CDKN2B
CDKN2C
CENPA
CRELD2
CTBP2
CTSV
CYLC2
DEAF1
E2F1
E4F1
EEF2
EFHC2
EGR1
EPHA2
EPHA3
EXOC2
FGFR4
FN1
FRAT2
FZR1
GALNT12
GAPDH
GGA1
GGA3
GLIS1
GLIS2
GMNN
GSPT1
H2BU1
HGF
HIF1A
HLA-DOB
HNRNPA2B1
HNRNPC
HNRNPU
HRAS
HSP90AA1
HSP90AB1
HSPA4
HSPA8
HUWE1
ISOC2
KAT5
LATS2
MAF1
MAP2K1
MAP2K5
MAP3K5
MAPK10
MAPK14
MAPK3
MAPK8
MCM10
MCM2
MCM5
MCM6
MDM2
MDM4
MMRN1
MTR
MYC
MYL12A
NAT2
NCL
NMI
NOP53
NPM1
NSD3
ORC4
PCNA
PDCD6
PDGFRA
PEX19
PPP1R9B
PRKCA
PSMC3
PTP4A3
RAF1
RASA1
RASSF1
RBM26
RIN2
RPL11
RPS7
RUVBL2
SEC61B
SERTAD1
SFRP4
SIVA1
SIX2
SLC4A1
SMARCA4
SNRPA
SNRPB
SOX3
SOX4
STK11
TBRG1
TDRD7
TEAD2
TERT
TFDP1
TGFB1
TMEFF1
TMOD1
TP53
TP63
TPI1
TRIM28
TRIP12
TSC1
TUBA1A
TUBA1C
TUBB
TUBB4B
UBE2A
UBE4B
UBL7
USP26
VAMP1
VHL
WRN
YY1
ZFP91
ZGRF1
ZNF227
ZNF410
ZNF420
ZNF687
ZUP1
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80 interacting genes:
ACTB
ACTL6A
AHR
AR
ARID1A
ARID1B
ARID2
BRCA1
BRWD1
CARM1
CBX5
CCNE1
CDK19
CDK8
CDKN2A
CDX2
CEBPA
CEBPB
CHD4
CHFR
CHMP5
CIITA
CREB1
CTNNB1
E2F6
ESR1
ETS2
FANCA
GATA1
GMNN
H2AX
H2BC21
H3-3A
H3C1
H3C14
H4C6
HSF1
HSF4
HSPB1
IKZF1
KLF1
MBD3
MDM2
MED17
MED6
MPHOSPH6
MRTFA
MYC
MYOCD
NR3C1
NR4A2
PABPN1
PALS2
PAX6
PBRM1
PHB
PTEN
RAP1A
RASSF1
RB1
RBL1
RBL2
RELB
RFXAP
SIN3A
SIN3B
SMARCB1
SMARCC1
SMARCE1
SOX4
SS18
SS18L1
STAT2
STAT3
STK11
SUMO2
TAF15
TMF1
TP53
ZMYND11
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Entrez ID |
1029 |
6597 |
HPRD ID |
02542 |
04459 |
Ensembl ID |
ENSG00000147889
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ENSG00000127616
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Uniprot IDs |
K7PML8
P42771
Q8N726
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A7E2E1
B3KNW7
P51532
Q9HBD4
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PDB IDs |
1A5E
1BI7
1DC2
2A5E
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2GRC
2H60
3UVD
5DKD
5EA1
6BGH
6HR2
6LTH
6LTJ
6SY2
6ZS2
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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