SMNDC1 and SNRNP200

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		SMNDC1	SNRNP200
Description		survival motor neuron domain containing 1	small nuclear ribonucleoprotein U5 subunit 200
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cajal Body Nuclear Speck	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Membrane U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 1 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Protein Binding	RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Apoptotic Process	Cis Assembly Of Pre-catalytic Spliceosome Spliceosome Conformational Change To Release U4 (or U4atac) And U1 (or U11) MRNA Splicing, Via Spliceosome Osteoblast Differentiation
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases			Retinitis pigmentosa (RP)
GWAS		Crohn's disease ( 23850713) Refractive error ( 32231278)
Interacting Genes		4 interacting genes: H3-4 KPNB1 SNRNP200 SNRPB	34 interacting genes: APC BARD1 BCAS2 BRCA1 CHMP1B DHX38 DUX4 ECT2 EFTUD2 ERG GNMT GRB2 HNRNPA1 HSPB1 LSM8 MATR3 MEGF10 PIN1 PRPF3 PRPF31 PRPF8 PTEN RNF113A SF3B2 SF3B3 SMNDC1 SNRNP40 SNW1 SUMO2 UBE2I USP19 WBP4 YWHAB YWHAG
Entrez ID		10285	23020
HPRD ID		04627	03391
Ensembl ID		ENSG00000119953	ENSG00000144028
Uniprot IDs		O75940	O75643
PDB IDs		4A4F 4A4H	2Q0Z 3JCR 4F91 4F92 4F93 4KIT 5O9Z 5URJ 5URK 5URM 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6FF7 6ICZ 6QDV 6QW6 6QX9 6S8O 6S8Q 6S9I 7A5P
Enriched GO Terms of Interacting Partners?
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