CWC27 and FRA10AC1

Data Source:
BioGRID (two hybrid)

		CWC27	FRA10AC1
Description		CWC27 spliceosome associated cyclophilin	FRA10A associated CGG repeat 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Nucleus
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Cyclosporin A Binding	Protein Binding Phosphatase Activity
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding	Dephosphorylation
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Adult body size ( 32376654) Bladder cancer ( 27206850) Central corneal thickness ( 31798171 29760442) Diverticular disease ( 30177863) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Glucocorticoid-induced osteonecrosis (age 10 years and older) ( 26265699) Obesity-related traits ( 23251661) Refractive error ( 32231278) Systolic blood pressure ( 30224653) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532)	Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321) Cerebrospinal fluid AB1-42 levels ( 26252872 29274321) Refractive error ( 32231278)
Interacting Genes		4 interacting genes: CLK1 FRA10AC1 HMGA1 MORF4L1	28 interacting genes: ADPRS C7orf25 CHERP CWC27 EEF1D ESS2 GATD3A GDPD2 GLRX3 HABP4 IK KASH5 MAP3K12 MFAP1 MOB2 NKAP PLPPR4 PRPF3 PRPF40A SAP30BP SF3B2 THOC1 TRIM41 TTC14 U2AF1 VPS29 ZCCHC10 ZNF830
Entrez ID		10283	118924
HPRD ID		11541	12319
Ensembl ID		ENSG00000153015	ENSG00000148690
Uniprot IDs		D6REK3 Q6UX04	Q70Z53
PDB IDs		2HQ6 4R3E 5Z56 5Z58 6FF4 6FF7 6YVH
Enriched GO Terms of Interacting Partners?
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