POP7 and LAGE3

Data Source:
BioGRID (two hybrid)

		POP7	LAGE3
Description		POP7 homolog, ribonuclease P/MRP subunit	L antigen family member 3
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GO Annotations	Cellular Component	Ribonuclease MRP Complex Nucleus Nucleoplasm Nucleolus Cytoplasm Multimeric Ribonuclease P Complex Intracellular Membrane-bounded Organelle	EKC/KEOPS Complex Nucleus Nucleoplasm Cytoplasm Nuclear Body
	Molecular Function	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	Protein Binding
	Biological Process	TRNA 5'-leader Removal RRNA Processing TRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	TRNA Processing Biological_process Positive Regulation Of Transcription By RNA Polymerase II TRNA Threonylcarbamoyladenosine Metabolic Process
Pathways		tRNA processing in the nucleus	tRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Low density lipoprotein cholesterol levels ( 32154731) Medication use (thyroid preparations) ( 31015401) Pursuit maintenance gain in psychotic disorders ( 29064472) Red blood cell count ( 32888494 27863252) Schizophrenia ( 30285260)
Interacting Genes		9 interacting genes: APP C9orf72 HSPB1 LAGE3 RPP25 RPP25L RPP38 RPP40 SMN1	22 interacting genes: AKAP8L CYSRT1 GOLGA6L9 GON7 HSF2BP HYKK KRT40 KRTAP10-8 KRTAP6-3 MID2 MIPOL1 MKRN3 OSGEP PDE9A PLEKHJ1 PNMA1 POP7 PSMB9 TRIM23 TRIM27 TRIM55 VPS37C
Entrez ID		10248	8270
HPRD ID		09357	02087
Ensembl ID		ENSG00000172336	ENSG00000196976
Uniprot IDs		O75817	Q14657
PDB IDs		6AHR 6AHU 6CWX	6GWJ
Enriched GO Terms of Interacting Partners?
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