ALYREF and THOC6

Data Source:
BioGRID (affinity chromatography technology, pull down)

		ALYREF	THOC6
Description		Aly/REF export factor	THO complex 6
Image			No pdb structure
GO Annotations	Cellular Component	Transcription Export Complex Chromosome, Telomeric Region Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Speck Exon-exon Junction Complex Extracellular Exosome Catalytic Step 2 Spliceosome	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Chromosome, Telomeric Region Nucleus Nucleoplasm Nuclear Body Nuclear Speck
	Molecular Function	RNA Binding Protein Binding C5-methylcytidine-containing RNA Binding	RNA Binding
	Biological Process	Regulation Of DNA Recombination MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Export From Nucleus MRNA Export From Nucleus Viral Process MRNA 3'-end Processing Replication Fork Processing Positive Regulation Of DNA-templated Transcription, Elongation Viral MRNA Export From Host Cell Nucleus	RNA Export From Nucleus MRNA Export From Nucleus Apoptotic Process Central Nervous System Development RNA Splicing MRNA 3'-end Processing Negative Regulation Of Apoptotic Process Viral MRNA Export From Host Cell Nucleus
Pathways		Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS
Interacting Genes		11 interacting genes: AKT1 DDX39B ESR1 IL7R LEF1 MAGOH NXF1 PTEN RUNX2 THOC6 UPF3A	3 interacting genes: ALYREF DDX39B PTEN
Entrez ID		10189	79228
HPRD ID		09168	14504
Ensembl ID		ENSG00000183684	ENSG00000131652
Uniprot IDs		E9PB61 Q86V81	Q86W42
PDB IDs		3ULH
Enriched GO Terms of Interacting Partners?
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