TRIM10 and UBE2D4

Data Source:
BioGRID (two hybrid)

		TRIM10	UBE2D4
Description		tripartite motif containing 10	ubiquitin conjugating enzyme E2 D4 (putative)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Ubiquitin Ligase Complex Nucleus
	Molecular Function	Molecular_function Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Biological_process Regulation Of Gene Expression Protein Ubiquitination Erythrocyte Differentiation Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein K29-linked Ubiquitination Protein K27-linked Ubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Protein K6-linked Ubiquitination
Pathways		Interferon gamma signaling	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Anger ( 24489884) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) HIV-1 control ( 20041166) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Neuroticism ( 29255261) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)
Interacting Genes		17 interacting genes: GEM HGS LNX1 PRKAB2 PSMA1 SCNM1 TRIM35 TRIM44 TTC23 UBE2D1 UBE2D2 UBE2D3 UBE2D4 YPEL3 ZNF148 ZNF414 ZNF620	109 interacting genes: AMFR ARIH2 BFAR BIRC8 CADPS2 CHFR CNOT4 DAZAP2 DTX1 DTX2 DTX3 DTX3L DZIP3 H3C1 H4C1 IKBKG INCA1 ITCH LNX1 LRSAM1 MAGEA11 MAP3K1 MARCHF3 MDM2 MGRN1 MIB1 MID1 MID2 MKRN1 MKRN2 MKRN3 MUL1 MYBL2 MYLIP OTUB1 PHF7 PJA2 POLR2E PRKN RBCK1 RCHY1 REL RFWD3 RING1 RLIM RMND5B RNF10 RNF103 RNF11 RNF111 RNF114 RNF115 RNF125 RNF126 RNF13 RNF130 RNF138 RNF14 RNF150 RNF165 RNF166 RNF167 RNF181 RNF185 RNF2 RNF216 RNF26 RNF31 RNF38 RNF4 RNF43 RNF5 RNF7 SIAH1 STUB1 TOPORS TRAF6 TRAF7 TRIM10 TRIM17 TRIM2 TRIM23 TRIM25 TRIM27 TRIM3 TRIM31 TRIM35 TRIM38 TRIM39 TRIM43 TRIM45 TRIM5 TRIM50 TRIM54 TRIM62 TRIM8 UBA1 UBC UBE4A UBOX5 UBTD1 UBTD2 UFM1 UHRF2 UVSSA XIAP ZNRF1 ZNRF2 ZNRF4
Entrez ID		10107	51619
HPRD ID		05752	14242
Ensembl ID		ENSG00000204613	ENSG00000078967
Uniprot IDs		A0A1U9X8M5 Q9UDY6	A0A024RA90 Q9UQL0 Q9Y2X8
PDB IDs
Enriched GO Terms of Interacting Partners?
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