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ARPC3 and ARPC4
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
ARPC3
ARPC4
Description
actin related protein 2/3 complex subunit 3
actin related protein 2/3 complex subunit 4
Image
GO Annotations
Cellular Component
Nucleus
Cytosol
Arp2/3 Protein Complex
Focal Adhesion
Actin Cytoskeleton
Membrane
Lamellipodium
Filamentous Actin
Site Of Double-strand Break
Growth Cone Leading Edge
Extracellular Exosome
Nucleus
Cytosol
Arp2/3 Protein Complex
Site Of Double-strand Break
Cell Projection
Extracellular Exosome
Molecular Function
Structural Constituent Of Cytoskeleton
Protein Binding
Actin Filament Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Enzyme Binding
Protein-macromolecule Adaptor Activity
Actin Filament Binding
Biological Process
Arp2/3 Complex-mediated Actin Nucleation
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Ephrin Receptor Signaling Pathway
Membrane Organization
Actin Polymerization-dependent Cell Motility
Cellular Response To Nerve Growth Factor Stimulus
Actin Filament Polymerization
Arp2/3 Complex-mediated Actin Nucleation
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Actin Nucleation
Ephrin Receptor Signaling Pathway
Membrane Organization
Pathways
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
EPHB-mediated forward signaling
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
Clathrin-mediated endocytosis
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
EPHB-mediated forward signaling
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
Clathrin-mediated endocytosis
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Drugs
N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide
(2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide
(2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS
Automobile speeding propensity (
30643258
)
Bipolar disorder (
31043756
)
Femoral neck bone mineral density (
30172743
)
Interacting Genes
30 interacting genes:
ACTR3
ARAP1
ARPC4
BAG6
CCR10
CDKN2B
CETP
DUSP29
EFTUD2
FAM9A
GOLGA2
HOXA3
LATS1
LGALS4
LTA4H
MAPK6
NRIP1
OTUD5
POU2F1
PRMT1
RBBP8NL
RETREG3
RPS4X
SYBU
TARS3
THNSL2
WAS
WASF2
WASL
ZNF576
13 interacting genes:
ACTR2
ACTR3
ARPC1B
ARPC2
ARPC3
ARPC5
ARPC5L
CLK1
METTL21A
NELFCD
PNMA5
RNF130
WASL
Entrez ID
10094
10093
HPRD ID
09175
10368
Ensembl ID
ENSG00000111229
ENSG00000241553
Uniprot IDs
O15145
P59998
PDB IDs
6UHC
6YW6
6YW7
6UHC
6YW6
6YW7
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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