IL18BP and IL37

Data Source:
HPRD (in vitro)

		IL18BP	IL37
Description		interleukin 18 binding protein	interleukin 37
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Exosome	Extracellular Region Extracellular Space Nucleoplasm Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Interleukin-18 Binding Receptor Antagonist Activity	Cytokine Activity Interleukin-1 Receptor Binding Protein Binding
	Biological Process	Interleukin-18-mediated Signaling Pathway T-helper 1 Type Immune Response Cellular Response To Cytokine Stimulus Negative Regulation Of Signaling Receptor Activity	Inflammatory Response To Antigenic Stimulus Inflammatory Response Immune Response Positive Regulation Of Gene Expression Cytokine-mediated Signaling Pathway Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Regulation Of Inflammatory Response Cellular Response To Lipopolysaccharide Cellular Response To Cytokine Stimulus
Pathways		Interleukin-37 signaling Interleukin-18 signaling	Interleukin-37 signaling Interleukin-18 signaling
Drugs
Diseases
GWAS			Dysmenorrheic pain severity ( 29855537) Menstruation quality of life impact (dysmenorrhea) ( 29855537) Pain medicine use during menstruation ( 29855537) Pulmonary function ( 23932459) Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy) ( 24554482)
Interacting Genes		2 interacting genes: IL18 IL37	8 interacting genes: CASP1 CASP4 IL18BP IL18R1 PRKAB2 SMAD3 TRIM55 TRIM63
Entrez ID		10068	27178
HPRD ID		04984	05695
Ensembl ID		ENSG00000137496	ENSG00000125571
Uniprot IDs		A0A024R5G2 A0A024R5I1 A0A024R5M7 G3V1C5 O95998	Q9NZH6
PDB IDs			5HN1 6NCU
Enriched GO Terms of Interacting Partners?
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