TOM1 and PILRA

Data Source:
BioGRID (two hybrid)

		TOM1	PILRA
Description		target of myb1 membrane trafficking protein	paired immunoglobin like type 2 receptor alpha
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GO Annotations	Cellular Component	Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Membrane Azurophil Granule Membrane Specific Granule Membrane Extracellular Exosome	Plasma Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Protein Binding Clathrin Binding	Protein Binding MHC Class I Protein Binding
	Biological Process	Intracellular Protein Transport Endocytosis Signal Transduction Protein Transport Endosomal Transport Neutrophil Degranulation	Signal Transduction Viral Process Regulation Of Immune Response
Pathways		Neutrophil degranulation	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Cholesterol, total ( 24097068) HDL cholesterol ( 29404214) High density lipoprotein cholesterol levels ( 31217584) Hippocampal volume in mild cognitive impairment ( 29274321) Inflammatory bowel disease ( 28067908) Low density lipoprotein cholesterol levels ( 32154731) Multiple myeloma ( 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease ( 29748315) Total cholesterol levels ( 28334899) Ulcerative colitis ( 28067908) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Advanced age-related macular degeneration ( 26691988) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Red cell distribution width ( 32888494) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		21 interacting genes: APP CLTC DAZAP2 EEA1 ILVBL LITAF LRRC20 MAP3K1 MYO6 NAA11 NEDD4 PILRA PTBP2 RPS27 SMURF1 SSBP2 TOLLIP UBC UBE2D1 ZFYVE16 ZNF512B	10 interacting genes: DNPH1 FAM114A2 FCAR PAICS PFDN5 PTPN11 PTPN6 SORBS1 TOM1 UROD
Entrez ID		10043	29992
HPRD ID		05265	05631
Ensembl ID		ENSG00000100284	ENSG00000085514
Uniprot IDs		B3KUF5 O60784	Q9UKJ1
PDB IDs		1ELK 1WRD 2N2N 2N9D 6J56	3WUZ 3WV0 4NFB 5XO2 5XOF
Enriched GO Terms of Interacting Partners?
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