PDCD6 and ANXA11

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid, far western blotting, pull down)
HPRD (in vitro, two hybrid)

		PDCD6	ANXA11
Description		programmed cell death 6	annexin A11
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol COPII Vesicle Coat Cytoplasmic Vesicle Cul3-RING Ubiquitin Ligase Complex Extracellular Exosome Endoplasmic Reticulum Exit Site	Nuclear Envelope Nucleoplasm Cytoplasm Spindle Cytosol Membrane Midbody Melanosome Specific Granule Azurophil Granule Phagocytic Vesicle Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Magnesium Ion Binding Calcium Ion Binding Protein Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Protein Homodimerization Activity Protein-membrane Adaptor Activity Protein Dimerization Activity Calcium-dependent Protein Binding Ubiquitin Ligase-substrate Adaptor Activity	RNA Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding MHC Class II Protein Complex Binding S100 Protein Binding Calcium-dependent Protein Binding
	Biological Process	Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Endothelial Cell Migration Neural Crest Formation Neural Crest Cell Development Protein Ubiquitination Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of TOR Signaling Cellular Response To Heat Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Angiogenesis COPII Vesicle Coating Response To Calcium Ion Negative Regulation Of Protein Kinase B Signaling Apoptotic Signaling Pathway Positive Regulation Of Protein Monoubiquitination	Phagocytosis Cytokinetic Process Response To Calcium Ion
Pathways
Drugs		Calcium Zinc Calcium citrate Calcium Phosphate Calcium phosphate dihydrate Zinc acetate
Diseases
GWAS			Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Diabetic kidney disease ( 26305897) Sarcoidosis ( 22936702) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848)
Interacting Genes		22 interacting genes: ANXA11 ANXA7 BAG4 CDKN2A CPNE1 CPNE2 CPNE4 CUL3 FAS FASLG HEBP2 IGFALS MAP3K5 MAPK1IP1L PDCD6IP PEF1 PRR19 SEC31A SH3KBP1 TIMM22 VPS37C YWHAQ	18 interacting genes: ALG2 ARSA CDC42 CEP55 ENO2 EWSR1 FUBP1 HNRNPH3 KRTAP13-2 KRTAP6-2 NFKBID PDCD6 PLSCR1 S100A6 SRI TFG WWOX ZDHHC17
Entrez ID		10016	311
HPRD ID		03035	03983
Ensembl ID		ENSG00000249915	ENSG00000122359
Uniprot IDs		A0A024QZ42 A0A087WZ38 O75340 Q53FC3	P50995 Q5T0G8
PDB IDs		2ZN8 2ZN9 2ZND 2ZNE 2ZRS 2ZRT 3AAJ 3AAK 3WXA 5GQQ
Enriched GO Terms of Interacting Partners?
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