SBK3 and NOTO

Data Source:
BioGRID (two hybrid)

		SBK3	NOTO
Description		SH3 domain binding kinase family member 3	notochord homeobox
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein Phosphorylation	Heart Looping Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Embryonic Pattern Specification Dorsal/ventral Pattern Formation Neuron Differentiation Notochord Development Motile Cilium Assembly Regulation Of Cilium Assembly
Pathways
Drugs		Fostamatinib
Diseases
GWAS			General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435)
Interacting Genes		13 interacting genes: AIMP2 ATXN7L2 C1orf105 CRY2 DMAP1 EXOSC2 GATAD2B MBD3L2 NOTO POLDIP3 SMAD3 SNRNP35 TNNT1	31 interacting genes: ANKRD11 APOBEC1 BAG3 BANP BTF3 CCDC120 CEP19 CHAF1A EIPR1 ETV3L FAM9B FOXD2 FOXH1 GLYCTK HNRNPK IP6K3 KRT34 KRTAP19-7 KRTAP5-6 KRTAP6-1 KRTAP6-3 LDLRAP1 LRP10 MAGED1 MEIS2 NKX2-4 PIH1D2 POU4F2 SBK3 TTC23 UBTFL1
Entrez ID		100130827	344022
HPRD ID
Ensembl ID		ENSG00000231274	ENSG00000214513
Uniprot IDs		P0C264	A8MTQ0
PDB IDs
Enriched GO Terms of Interacting Partners?
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