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TRAT1

Description T cell receptor associated transmembrane adaptor 1
Image No pdb structure
GO Annotations Cellular Component
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • Centriolar Satellite
  • T Cell Receptor Complex
  • Mitotic Spindle
Molecular Function
  • Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity
  • Protein Binding
Biological Process
  • Negative Regulation Of Receptor Recycling
  • Adaptive Immune Response
  • Cellular Defense Response
  • Signal Transduction
  • Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
  • Positive Regulation Of Calcium-mediated Signaling
  • T Cell Receptor Signaling Pathway
  • Positive Regulation Of T Cell Receptor Signaling Pathway
  • Negative Regulation Of Transport
  • Positive Regulation Of Protein Kinase B Signaling
Pathways
  • PIP3 activates AKT signaling
  • Downstream TCR signaling
  • Constitutive Signaling by Aberrant PI3K in Cancer
  • PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Drugs
Diseases
GWAS
  • Autoimmune thyroid disease ( 32581359)
Interacting Genes 13 interacting genes: BDKRB1 CD247 CD3E FYN GRB2 LCK LCP2 LYN PIK3R1 SEC22A SRC TRA TRB
Entrez ID 50852
HPRD ID 05392
Ensembl ID ENSG00000163519
Uniprot IDs C9JF66 Q6PIZ9
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025