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NFATC3
Description
nuclear factor of activated T cells 3
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Cytoplasm
Cytosol
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Transcription Factor Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Cytokine Production
Regulation Of Transcription By RNA Polymerase II
Inflammatory Response
Multicellular Organism Development
Calcineurin-NFAT Signaling Cascade
Fc-epsilon Receptor Signaling Pathway
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation
Pathways
Calcineurin activates NFAT
Calcineurin activates NFAT
FCERI mediated Ca+2 mobilization
CLEC7A (Dectin-1) induces NFAT activation
Drugs
Diseases
GWAS
Chronotype (
30696823
)
Estimated glomerular filtration rate (
31015462
)
Refractive error (
32231278
)
Schizophrenia (
25056061
29483656
)
Urate levels (
31578528
)
Novel Interacting Genes
7 novel interacting genes:
CALB2
CELSR2
KCNJ3
MYOCD
SEC24A
SNX20
TOR1B
Interacting Genes
6 interacting genes:
CDK6
CSNK1A1
FOS
MAPK8
MAPK9
TTF1
Entrez ID
4775
HPRD ID
04077
Ensembl ID
ENSG00000072736
Uniprot IDs
B5B2S0
B5B2S1
Q12968
PDB IDs
2XRW
2XS0
Enriched GO Terms of Interacting Partners
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