NFATC3 and SNX20

Data Source:
BioGRID (affinity chromatography technology)

		NFATC3	SNX20
Description		nuclear factor of activated T cells 3	sorting nexin 20
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol	Nucleoplasm Plasma Membrane Early Endosome Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3-phosphate Binding
	Biological Process	Cytokine Production Regulation Of Transcription By RNA Polymerase II Inflammatory Response Multicellular Organism Development Calcineurin-NFAT Signaling Cascade Fc-epsilon Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Pri-miRNA Transcription By RNA Polymerase II Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation	Protein Transport
Pathways		Calcineurin activates NFAT Calcineurin activates NFAT FCERI mediated Ca+2 mobilization CLEC7A (Dectin-1) induces NFAT activation
Drugs
Diseases
GWAS		Chronotype ( 30696823) Estimated glomerular filtration rate ( 31015462) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Urate levels ( 31578528)	Asthma (childhood onset) ( 31036433) Crohn's disease ( 28008999 28067908 22412388) Inflammatory bowel disease ( 28008999 28067908)
Interacting Genes		6 interacting genes: CDK6 CSNK1A1 FOS MAPK8 MAPK9 TTF1	8 interacting genes: ALAS1 FAM9B GMCL1 KLHL12 MAGEA11 SPDEF TACC3 TFIP11
Entrez ID		4775	124460
HPRD ID		04077	15401
Ensembl ID		ENSG00000072736	ENSG00000167208
Uniprot IDs		B5B2S0 B5B2S1 Q12968	Q7Z614
PDB IDs		2XRW 2XS0
Enriched GO Terms of Interacting Partners?
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