NFATC3 and TOR1B

Data Source:
HPRD (in vitro)

		NFATC3	TOR1B
Description		nuclear factor of activated T cells 3	torsin family 1 member B
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Lumen Nuclear Membrane Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	Protein Binding ATP Binding ATPase Activity Kinesin Binding Identical Protein Binding
	Biological Process	Cytokine Production Regulation Of Transcription By RNA Polymerase II Inflammatory Response Multicellular Organism Development Calcineurin-NFAT Signaling Cascade Fc-epsilon Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Pri-miRNA Transcription By RNA Polymerase II Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation	Response To Unfolded Protein Endoplasmic Reticulum Organization Protein Localization To Nucleus Chaperone Cofactor-dependent Protein Refolding Nuclear Membrane Organization
Pathways		Calcineurin activates NFAT Calcineurin activates NFAT FCERI mediated Ca+2 mobilization CLEC7A (Dectin-1) induces NFAT activation	Cargo recognition for clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Chronotype ( 30696823) Estimated glomerular filtration rate ( 31015462) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Urate levels ( 31578528)
Interacting Genes		6 interacting genes: CDK6 CSNK1A1 FOS MAPK8 MAPK9 TTF1	1 interacting genes: TOR1A
Entrez ID		4775	27348
HPRD ID		04077	16270
Ensembl ID		ENSG00000072736	ENSG00000136816
Uniprot IDs		B5B2S0 B5B2S1 Q12968	O14657
PDB IDs		2XRW 2XS0
Enriched GO Terms of Interacting Partners?
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