Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
SOCS2
Description
suppressor of cytokine signaling 2
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Phosphatidylinositol 3-kinase Complex
Molecular Function
Growth Hormone Receptor Binding
Insulin-like Growth Factor Receptor Binding
Protein Binding
JAK Pathway Signal Transduction Adaptor Activity
1-phosphatidylinositol-3-kinase Regulator Activity
Biological Process
Regulation Of Cell Growth
Receptor Signaling Pathway Via JAK-STAT
Lactation
Regulation Of Signal Transduction
Protein Ubiquitination
Response To Estradiol
Cellular Response To Hormone Stimulus
Intracellular Signal Transduction
Interleukin-7-mediated Signaling Pathway
Negative Regulation Of Multicellular Organism Growth
Negative Regulation Of Apoptotic Process
Regulation Of Phosphatidylinositol 3-kinase Activity
Post-translational Protein Modification
Positive Regulation Of Neuron Differentiation
Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT
Phosphatidylinositol Phosphorylation
Growth Hormone Receptor Signaling Pathway
Mammary Gland Alveolus Development
Pathways
Interleukin-7 signaling
Neddylation
Negative regulation of FLT3
Growth hormone receptor signaling
Drugs
Diseases
GWAS
Height (
28552196
20881960
25282103
25429064
23563607
31562340
18391951
18391952
)
Hepatic lipid content in extreme obesity (
25246029
)
Joint damage in rheumatoid arthritis (
31596875
)
Pubertal anthropometrics (
23449627
)
Type 2 diabetes (
30054458
)
Novel Interacting Genes
1 novel interacting genes:
TBK1
Interacting Genes
19 interacting genes:
ARFIP2
BMI1
EGFR
EPOR
ERBB3
ERBB4
GHR
IGF1R
INSR
KIT
MET
PLA2G1B
PRLR
PTK2
RYBP
SOCS3
STK16
TPD52
YES1
Entrez ID
8835
HPRD ID
05490
Ensembl ID
ENSG00000120833
Uniprot IDs
A0A024RBD2
O14508
PDB IDs
2C9W
4JGH
5BO4
6I4X
6I5J
6I5N
Enriched GO Terms of Interacting Partners
?
Tagcloud
?