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NKX2-1
Description
NK2 homeobox 1
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Intronic Transcription Regulatory Region Sequence-specific DNA Binding
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
Enzyme Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Neuron Migration
Regulation Of Transcription By RNA Polymerase II
Phospholipid Metabolic Process
Axon Guidance
Brain Development
Endoderm Development
Locomotory Behavior
Response To Hormone
Positive Regulation Of Gene Expression
Negative Regulation Of Epithelial To Mesenchymal Transition
Globus Pallidus Development
Hippocampus Development
Cerebral Cortex Cell Migration
Forebrain Dorsal/ventral Pattern Formation
Forebrain Neuron Fate Commitment
Cerebral Cortex GABAergic Interneuron Differentiation
Pituitary Gland Development
Cell Differentiation
Lung Development
Negative Regulation Of Cell Migration
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Thyroid Gland Development
Forebrain Development
Developmental Induction
Leydig Cell Differentiation
Positive Regulation Of Circadian Rhythm
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Rhythmic Process
Anatomical Structure Formation Involved In Morphogenesis
Oligodendrocyte Differentiation
Lung Saccule Development
Epithelial Tube Branching Involved In Lung Morphogenesis
Club Cell Differentiation
Type II Pneumocyte Differentiation
Pathways
Drugs
Diseases
Choreoathetosis, hypothyroidism, and neonatal respiratory distress
GWAS
Differentiated thyroid cancer (
28703219
)
Height (
18391950
)
Menarche (age at onset) (
23667675
29773799
)
Papillary thyroid cancer (
28703219
)
Thyroid cancer (
19198613
)
Novel Interacting Genes
1 novel interacting genes:
JAKMIP1
Interacting Genes
15 interacting genes:
CALR
CAVIN1
CREBBP
FOXA1
GATA6
HIPK2
MAPK1
NCOA1
NCOA2
NCOA3
PAX8
RARA
RELA
TDG
WWTR1
Entrez ID
7080
HPRD ID
02798
Ensembl ID
ENSG00000136352
Uniprot IDs
P43699
PDB IDs
Enriched GO Terms of Interacting Partners
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