SPTBN2

Description		spectrin beta, non-erythrocytic 2
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GO Annotations	Cellular Component	Extracellular Space Cytosol Spectrin Apical Plasma Membrane Neuronal Cell Body Parallel Fiber To Purkinje Cell Synapse Presynapse Glutamatergic Synapse Postsynaptic Spectrin-associated Cytoskeleton
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Phospholipid Binding Cadherin Binding Structural Constituent Of Synapse
	Biological Process	MAPK Cascade Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cytoskeleton Organization Axon Guidance Synapse Assembly Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cerebellar Purkinje Cell Layer Morphogenesis Adult Behavior Multicellular Organism Growth Actin Filament Capping Postsynapse Organization
Pathways		MHC class II antigen presentation NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins RAF/MAP kinase cascade COPI-mediated anterograde transport
Drugs
Diseases		Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		Bipolar disorder ( 28115744 21926972 31043756)
Interacting Genes		11 interacting genes: ACTA1 ACTB ACTR1A ADRB2 APC CELSR3 DCTN1 MINK1 SPTA1 SPTAN1 UNC13B
Entrez ID		6712
HPRD ID		05404
Ensembl ID		ENSG00000173898
Uniprot IDs		O15020
PDB IDs		1WJM 1WYQ 6ANU
Enriched GO Terms of Interacting Partners?
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