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PAK5

Description p21 (RAC1) activated kinase 5
Image
GO Annotations Cellular Component
  • Nucleoplasm
  • Cytoplasm
  • Mitochondrion
  • Synapse
Molecular Function
  • Protein Serine/threonine Kinase Activity
  • Protein Binding
  • ATP Binding
  • Protein Serine Kinase Activity
  • Protein Threonine Kinase Activity
Biological Process
  • Regulation Of Cell Growth
  • Protein Phosphorylation
  • Apoptotic Process
  • Cytoskeleton Organization
  • Signal Transduction
  • Learning
  • Memory
  • Locomotory Behavior
  • Cell Population Proliferation
  • Cell Migration
  • Stress-activated Protein Kinase Signaling Cascade
  • Activation Of Protein Kinase Activity
  • Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
  • Activation of RAC1
Drugs
  • Fostamatinib
Diseases
GWAS
  • Atopy ( 28927820)
  • Plasma factor V levels in venous thrombosis (conditioned on rs6027) ( 31271701)
Interacting Genes 34 interacting genes: ARHGEF19 ARMC7 ATPAF2 BAD CARD9 CATSPER1 CCDC57 CCNG1 CDC42 CRBN CSNK1D DDX6 DNPEP EMD ENKD1 EXOSC1 FHL3 GCC1 INKA1 LENG1 LNX1 LZTS2 MYO15B NTAQ1 PDLIM7 PRPF31 PSMF1 PTPN21 RAC1 RHOJ SORBS3 TSGA10 TUBGCP4 UXT
Entrez ID 57144
HPRD ID 06423
Ensembl ID ENSG00000101349
Uniprot IDs B0AZM9 Q9P286
PDB IDs 2F57
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025