Wiki-MPM

  • About
  • Search
  • Browse
  • People
  • Funding
  • Updates

KNL1

Description kinetochore scaffold 1
Image
GO Annotations Cellular Component
  • Condensed Chromosome Kinetochore
  • Acrosomal Vesicle
  • Nucleus
  • Nucleoplasm
  • Cytosol
  • Nuclear Body
Molecular Function
  • Protein Binding
Biological Process
  • Acrosome Assembly
  • Attachment Of Spindle Microtubules To Kinetochore
  • Negative Regulation Of Phosphatase Activity
  • CENP-A Containing Nucleosome Assembly
  • Protein Localization To Kinetochore
  • Cell Division
Pathways
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • RHO GTPases Activate Formins
  • Deposition of new CENPA-containing nucleosomes at the centromere
  • Mitotic Prometaphase
  • EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
  • Anxiety and stress-related disorders ( 31116379)
Novel Interacting Genes 1 novel interacting genes: PAK6
Interacting Genes 6 interacting genes: BUB1 BUB1B DSN1 MIS12 PPP1CA TTK
Entrez ID 57082
HPRD ID 10634
Ensembl ID ENSG00000137812
Uniprot IDs Q8NG31
PDB IDs 3SI5 4A1G 4NF9 4NFA
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025