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PRKAB1
Description
protein kinase AMP-activated non-catalytic subunit beta 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Nucleotide-activated Protein Kinase Complex
Molecular Function
Protein Kinase Activity
Protein Binding
Protein Kinase Binding
Biological Process
Protein Phosphorylation
Fatty Acid Biosynthetic Process
Cell Cycle Arrest
Signal Transduction
Positive Regulation Of Gene Expression
Macroautophagy
Regulation Of Macroautophagy
Nail Development
Regulation Of Catalytic Activity
Regulation Of Primary Metabolic Process
Positive Regulation Of Cold-induced Thermogenesis
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Macroautophagy
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of TP53 Activity through Phosphorylation
Lipophagy
Activation of AMPK downstream of NMDARs
Drugs
Adenosine phosphate
Adenosine phosphate
Metformin
Acetylsalicylic acid
Fostamatinib
Diseases
GWAS
Basophil count (
32888494
)
Inflammatory bowel disease (
26192919
)
Lymphocyte percentage of white cells (
32888494
)
Neutrophil count (
32888494
)
Plateletcrit (
32888494
)
Ulcerative colitis (
26192919
)
White blood cell count (
32888494
)
Interacting Genes
12 interacting genes:
ACACA
AGL
APP
F10
GRB2
MAP3K7
MAPK6
NDUFA7
PRKAA1
PRKAA2
PRKAG1
PRKAG2
Entrez ID
5564
HPRD ID
04116
Ensembl ID
ENSG00000111725
Uniprot IDs
A0A024RBN1
Q9Y478
PDB IDs
4CFE
4CFF
4ZHX
5EZV
5ISO
6B1U
6C9F
6C9G
6C9H
6C9J
Enriched GO Terms of Interacting Partners
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