PLCB2

Description		phospholipase C beta 2
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GO Annotations	Cellular Component	Cytosol
	Molecular Function	Phosphatidylinositol Phospholipase C Activity Phospholipase C Activity Calcium Ion Binding Protein Binding
	Biological Process	Phospholipid Metabolic Process G Protein-coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Wnt Signaling Pathway, Calcium Modulating Pathway Lipid Catabolic Process Inositol Phosphate Metabolic Process Phosphatidylinositol Metabolic Process Phosphatidylinositol-mediated Signaling Sensory Perception Of Bitter Taste
Pathways		PLC beta mediated events PLC beta mediated events Synthesis of IP3 and IP4 in the cytosol Acetylcholine regulates insulin secretion Acetylcholine regulates insulin secretion Ca2+ pathway G alpha (q) signalling events G alpha (q) signalling events G beta:gamma signalling through PLC beta Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion Presynaptic function of Kainate receptors
Drugs
Diseases
GWAS		Chronic kidney disease ( 30226566) Coronary artery disease ( 30402224) Hypertension ( 30226566) Ischemic stroke ( 29930801) Myocardial infarction ( 30226566) Neutrophil count ( 32888494) Schizophrenia ( 25056061 29483656) White blood cell count ( 32888494)
Novel Interacting Genes		11 novel interacting genes: - FAM98B GCHFR MTAP NEK2 PDIA3 PKD1L1 SOCS5 SPP1 THBS1 TRIB3
Interacting Genes		7 interacting genes: GNAQ MAP2K3 MAP2K6 SLC9A3R1 SNCA TRPC3 TRPM7
Entrez ID		5330
HPRD ID		04985
Ensembl ID		ENSG00000137841
Uniprot IDs		Q00722 Q59F77 Q9BVT6
PDB IDs		2FJU 2ZKM
Enriched GO Terms of Interacting Partners?
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