PLA2G5

Description		phospholipase A2 group V
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GO Annotations	Cellular Component	Extracellular Region Golgi Apparatus Plasma Membrane Early Phagosome Phagolysosome Recycling Endosome
	Molecular Function	Calcium Ion Binding Phospholipid Binding Calcium-dependent Phospholipase A2 Activity Calcium-independent Phospholipase A2 Activity Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine) Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)
	Biological Process	Fatty Acid Metabolic Process Phospholipid Metabolic Process Phosphatidic Acid Biosynthetic Process Positive Regulation Of Phospholipase Activity Positive Regulation Of Macrophage Derived Foam Cell Differentiation Leukotriene Biosynthetic Process Low-density Lipoprotein Particle Remodeling Phosphatidylcholine Catabolic Process Cardiolipin Acyl-chain Remodeling Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylinositol Acyl-chain Remodeling Phosphatidylserine Acyl-chain Remodeling Phosphatidylcholine Acyl-chain Remodeling Phosphatidylethanolamine Acyl-chain Remodeling Arachidonic Acid Secretion Positive Regulation Of Phagocytosis Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Immune Complex Clearance By Monocytes And Macrophages Phagosome-lysosome Fusion Positive Regulation Of Opsonization Positive Regulation Of Antifungal Innate Immune Response Positive Regulation Of Phagosome Maturation
Pathways		Acyl chain remodelling of PC Acyl chain remodelling of PS Acyl chain remodelling of PE Acyl chain remodelling of PI Acyl chain remodelling of PG Synthesis of PA
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP ( 31070471)
Novel Interacting Genes		2 novel interacting genes: GALE STC2
Interacting Genes		1 interacting genes: PLA2G4A
Entrez ID		5322
HPRD ID		03117
Ensembl ID		ENSG00000127472
Uniprot IDs		P39877
PDB IDs		2GHN
Enriched GO Terms of Interacting Partners?
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